Spirulinaeffect on modulation of toxins provided by food, impact on hepatic and renal functions

Abstract

Spirulina platensis, is an alga rich in phycocyanin (potent antioxidant), is effective in regulating the balance of oxidative stress. The objective of this study is to observe the impact of ingestion of a highly oxidised vegetable oil, by rats of Wistar strain. Finally, we observe the effect of Spirulina used as an antioxidant treatment, on rats having ingested a diet rich in highly oxidised oil. Physiological, biochemical and histological studies have been carried out; the oxidative stress parameters evaluated and a dosing of Cytochrome P450 2E1 was finally carried out. Following the introduction of highly oxidised vegetable oil, rats showed deterioration in their metabolic state, an imbalance in the balance of oxidative stress, an increase in serum concentrations of Cytochrome P450 2E1 and significant hepatic lesions. The administration of a daily dose of Spirulina reduces the deleterious effect of oxidative stress induced by a diet enriched with lipid peroxides.

Phycobiliproteins: Structural aspects, functional characteristics, and biotechnological perspectives

“… Diminish the risk of pathologies related to oxidative stress due to high oxidize oil consumption. [115] Spirulina sp. / Lengthening delivery of PC, encapsulated in poly(ethylene glycol)-b-(poly(l-glutamic acid)-g-polyethylenimine nano-carrier, through the abdominal subcutaneous injection in rats.…”

Irvingia Fat Ageing: Study of Chemical Characteristics Related to MIR Spectroscopy

“…The same behavior is noticed for the other sample under the same conditions of conservation. We can thus suspect that there is elongation of the carbon chains of the FA [14] during the ageing of the Irvingia fat and these whatever the conditions of conservation.…”