<i>Tabanus importunus</i>, vecteur mécanique expérimental de<i>Trypanosoma vivax</i>en Guyane Française

Raymond, Hugues-Louis

doi:10.1051/parasite/1990651044

Cited by 14 publications

(6 citation statements)

References 7 publications

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“…(Levine 1973). Mechanical transmission across cows has been experimentally demonstrated for the tabanids Cryptotylus unicolor (Ferenc et al 1988apud Dwinger & Hall 2000, and Tabanus importunus (Raymond 1990) in French Guiana, and for Tabanus nebulosus in Colombia (Otte & Abuabara 1991). Although it has been proposed that the parasite might be cyclically transmitted in South America by an unknown vector other than Glossina (Wells 1972), no evidence is available to support this hypothesis.…”

Section: Transmissionmentioning

confidence: 85%

Trypanosoma (Duttonella) vivax: its biology, epidemiology, pathogenesis, and introduction in the New World - a review

Osório

Madruga

Desquesnes

et al. 2008

Mem. Inst. Oswaldo Cruz

171

121

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Section: Transmissionmentioning

confidence: 85%

Trypanosoma (Duttonella) vivax: its biology, epidemiology, pathogenesis, and introduction in the New World - a review

Osório

Madruga

Desquesnes

et al. 2008

Mem. Inst. Oswaldo Cruz

171

121

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“…One of its main particularities that can explain its capacity to emerge in areas free from tsetse flies is its ability to also be transmitted mechanically by a broad spectra of haematophagous insects [5], [15]–[17]. We have previously developed experimental models of T. vivax infection using mice infected with the ILRAD1392 reference strain [9].…”

Section: Discussionmentioning

confidence: 99%

Non-Invasive In Vivo Study of the Trypanosoma vivax Infectious Process Consolidates the Brain Commitment in Late Infections

et al. 2013

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Trypanosoma vivax, one of the leading parasites responsible for Animal African Trypanosomosis (Nagana), is generally cyclically transmitted by Glossina spp. but in areas devoid of the tsetse flies in Africa or in Latin American countries is mechanically transmitted across vertebrate hosts by other haematophagous insects, including tabanids. We followed on from our recent studies on the maintenance of this parasite in vivo and in vitro, and its genetic manipulation, by constructing a West African IL1392 T. vivax strain that stably expresses firefly luciferase and is fully virulent for immunocompetent mice. We report here on a study where murine infection with this strain was monitored in vivo using a non-invasive method. Study findings fully support the use of this strain in the assessment of parasite dynamics in vivo since a strong correlation was found between whole body light emission measured over the course of the infection and parasitemia determined microscopically. In addition, parasitemia and survival rates were very similar for mice infected by the intraperitoneal and sub-cutaneous routes, except for a longer prepatent period following sub-cutaneous inoculation with the parasite. Our results clearly show that when administered by the subcutaneous route, the parasite is retained few days in the skin close to the inoculation site where it multiplies before passing into the bloodstream. Ex vivo bioluminescence analyses of organs isolated from infected mice corroborated our previous histopathological observations with parasite infiltration into spleen, liver and lungs. Finally, our study reinforces previous observations on the presence of the parasite in the central nervous system and consequently the brain commitment in the very late phases of the experimental infection.

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“…Since T. vivax does not have a cyclical development in the potential vectors (Tabanidae and Stomoxidae), it is common to hear that this parasite and T. evansi are transmitted by mechanical inoculators and not by vectors. Mechanical transmission from one bovine to another has been successfully achieved with the tabanids Cryptotylus unicolor, 39 and Tabanus importunus 40 in French Guyana and with Tabanus nebulosus in Colombia. 41 In Brazil T. vivax was reported for the first time by Shaw and Lainson 42 in a water buffalo ( Bubalis bubalis ) from the vicinity of the city of Belém, state of Pará.…”

Section: Trypanosoma Vivaxmentioning

confidence: 99%

Animal Trypanosomiasis in South America: Current Status, Partnership, and Information Technology

Dávila

Silva²

2000

Annals of the New York Academy of Sciences

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Animal trypanosome species of economical importance in South America include T. vivax and T. evansi. Both species are described in Brazil, Bolivia, Colombia, French Guyana, Peru, Suriname, and Venezuela. In Argentina and Guyana, only T. evansi and T. vivax are found, respectively. Our studies on T. vivax indicated that the parasite was spreading around 1.3 km per day in Bolivia. We found severe leukopenia in bovines from Pantanal (Brazil) and the Department of Santa Cruz (Bolivia). Because it can cause immunosupression, the importance of trypanosomiasis control in ensuring success of vaccination campaigns against foot and mouth disease (FMD) in the Pantanal and Bolivia should be considered. The use of one needle for several animals during FMD campaigns in Brazil and Bolivia could also contribute to the spread of T. vivax. The anticipated losses due to T. vivax could exceed $160 million, assuming there are 11 million head of cattle in the Brazilian Pantanal and Bolivian lowlands. International collaboration among research institutes is needed to deal with these diseases and parasites. Previous efforts using information technologies resulted in the creation of two discussion lists (Tryplink and Trypan), the edition of the on‐line version of Trypnews and Internet conferences.

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Tabanus importunus, vecteur mécanique expérimental deTrypanosoma vivaxen Guyane Française

Cited by 14 publications

References 7 publications

Trypanosoma (Duttonella) vivax: its biology, epidemiology, pathogenesis, and introduction in the New World - a review

Trypanosoma (Duttonella) vivax: its biology, epidemiology, pathogenesis, and introduction in the New World - a review

Non-Invasive In Vivo Study of the Trypanosoma vivax Infectious Process Consolidates the Brain Commitment in Late Infections

Animal Trypanosomiasis in South America: Current Status, Partnership, and Information Technology

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