I.V. regional guanethidine vs. reserpine for pain relief in reflex Sympathetic Dystrophy (RSD); A controlled, randomized, double-blind, crossover study

Lief, Philip A.; Reisman, R. M.; Rocco, Angelo G.; McKay, Warren R.; Kaul, Alan F.; Benfell, Kathleen

doi:10.1016/0304-3959(87)91482-5

Pain

1987

DOI: 10.1016/0304-3959(87)91482-5

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I.V. regional guanethidine vs. reserpine for pain relief in reflex Sympathetic Dystrophy (RSD); A controlled, randomized, double-blind, crossover study

Philip A. Lief¹,

R. M. Reisman²,

Angelo G. Rocco³

et al.

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1990

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Intravenous regional sympatholysis: A double-blind comparison of guanethidine, reserpine, and normal saline

Blanchard¹,

Ramamurthy²,

Walsh³

et al. 1990

Journal of Pain and Symptom Management

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This double-blind, randomized study was designed to compare the effectiveness of intravenous regional sympatholysis using guanethidine, reserpine and normal saline. Twenty-one patients with reflex sympathetic dystrophy of an upper or lower extremity were enrolled and received intravenous regional blockade (IVRB) with one of the three medications. There was significant pain relief in all three groups at 30 min. There were no significant differences among the three groups in the degree of pain relief, the number of patients obtaining pain relief in the 30 min after the block, or the number of patients reporting more than 50% pain relief for more than 24 hr. The saline group's high rate of pain relief could be partially due to a mechanism of tourniquet-induced analgesia.

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Intravenous regional sympatholysis: A double-blind comparison of guanethidine, reserpine, and normal saline

Blanchard¹,

Ramamurthy²,

Walsh³

et al. 1990

Journal of Pain and Symptom Management

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show abstract

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I.V. regional guanethidine vs. reserpine for pain relief in reflex Sympathetic Dystrophy (RSD); A controlled, randomized, double-blind, crossover study

Cited by 1 publication

References 0 publications

Intravenous regional sympatholysis: A double-blind comparison of guanethidine, reserpine, and normal saline

Intravenous regional sympatholysis: A double-blind comparison of guanethidine, reserpine, and normal saline

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