<i>Vernonia amygdalina</i> Del: A Mini Review

Danladi, Suleiman; Hassan, Mohammed A.; Masa’ud, Idris Aliyu; Ibrahim, Umar

doi:10.5958/0974-360x.2018.00768.0

Cited by 14 publications

(7 citation statements)

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“… Cough Antimicrobial, antimalarial, antithrombotic, antioxidant, antipyretic, analgesic, anti-diabetic, laxative, immunomodulatory, hypoglycemic, anti-inflammatory, antiviral, antifertility, anticancer, antihelmintic, cathartic, antifungal and antibacterial activities Safe LD 50 - 5152.3 mg/kg LD 50 - 3721 mg/kg. Momoh et al (2012) ; Chan et al (2016) ; Alara et al (2017) ; Tijjani et al (2017) ; Danladi et al (2018) ; Inusa et al (2018) ; Asante et al (2019) Bignoniaceae Kigella africana (Lam.) Benth Pneumonia Anti-plasmodial, antiviral, anticancer, antiulcer, antidiarrheal, antimicrobial, analgesic, antimicrobial, antioxidant, anti-trypanosomal, wound healing and anti-inflammatory activities.…”

Section: Methodsmentioning

confidence: 99%

Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19

Nyagumbo¹,

Pote²,

Shopo³

et al. 2022

Physics and Chemistry of the Earth, Parts A/B/C

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Section: Methodsmentioning

confidence: 99%

Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19

Nyagumbo¹,

Pote²,

Shopo³

et al. 2022

Physics and Chemistry of the Earth, Parts A/B/C

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“…A. australe Flavonoids, melampolides, saponins and tannins Antibacterial, antioxidant and cytotoxicity Sánchez et al 2009, Mallmann et al 2018 Alkaloids, cardiac glycosides, essential oils, flavonoids, phenols, saponins, tannins and terpenoids Antimicrobial, antiviral, anti-inflammatory, antimalarial and antioxidant Patil et al 2011, Muleya et al 2014, Van de Venter et al 2014, Adeogun et al 2018, Falowo et al 2019, Kane et al 2019 Alkaloids, alkanes, anthraquinones, esters, fatty acid, flavonoids, phenolics and terpenoids Antimicrobial, antiviral, antimalarial and cytotoxicity Cos et al 2002, Sesisubi et al 2010, Kuria 2014, Kuria et al 2015 Zdero et al 1991, Motsei et al 2003, Omosa et al 2019, Maroyi 2020c C. benedicta Essential oils, flavonoids, lactones, tannins and terpenoids Antimicrobial, anticancer, antidiabetic, anti-inflammatory, antioxidant, antinociceptive and wound healing Analgesic, anthelminthic, antibacterial, antifungal, anticonvulsant, anti-inflammatory, antioxidant, antiprotozoal, antipyretic, antispasmodic andcytotoxicity Akinmoladun et al 2007, Ngozi et al 2009, Odutayo et Momoh et al 2012, Chan et al 2016, Alara et al 2017, Tijjan et al 2017, Danladi et al 2018, Inusa et al 2018, Asante et al 2019, Kaur et al 2019 The floristic region with the highest number of reports of medicinal Asteraceae species in Zimbabwe is the central region (48, 96.0%), followed by eastern (45, 90.0%), northern (42, 84.0%), southern (33, 66.0%) Zimbabwe, whilst western Zimbabwe (32, 64.0%) has the lowest number (Fig. 6).…”

Section: Phytochemistry Pharmacological Activities Referencesmentioning

confidence: 99%

Medicinal uses of the Asteraceae family in Zimbabwe: A historical and ecological perspective

Maroyi

2023

Ethnobot. Res. App.

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Background: Several plant species belonging to the Asteraceae family are widely used as sources of traditional medicines. The current study was aimed at providing a systematic review of ethnomedicinal, phytochemical and pharmacological properties of Asteraceae species used as sources of traditional medicines in Zimbabwe.Methods: Information related to the ethnomedicinal, phytochemical and pharmacological properties of Asteraceae species was systematically collected using relevant keywords from online databases such as BioMed Central, Web of Science, Springerlink, Google Scholar, Scielo, PubMed, Science Direct, ACS Publications, Scopus and JSTOR, books, dissertations, theses, scientific reports and herbarium specimens.Results: This study showed that 50 species are traditionally used to manage human and animal diseases in Zimbabwe. These species are used as traditional medicines against 51 medical conditions, mainly used in the treatment of gastro-intestinal problems (34 use reports) and respiratory problems (28 use reports). Aspilia pluriseta, Baccharoides adoensis, Bidens pilosa, Brachylaena discolor var. rotundata, Dicoma anomala, Erythrocephalum zambesianum, Gymnanthemum amygdalinum, G. coloratum, Helichrysum caespititium, Inula glomerata, Laggera crispata, Linzia glabra, Lopholaena coriifolia, Schkuhria pinnata, Senecio coronatus, S. latifolius and Tagetes minuta have the highest number of medicinal uses. Majority of the documented species are characterized by flavonoids (46.0%), terpenoids (44.0%), tannins (40.0%), alkaloids (34.0%), saponins (26.0%), essential oils (24.0%) and glycosides (20.0%).Conclusions: Further phytochemical and pharmacological studies would be of great interest for assessment of ethnopharmacological properties of Asteraceae species used as sources of traditional medicines.

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“…The species' secondary metabolites, which include saponins, tannins, alkaloids, and glycosides, are anti-dietary components. These constituents are the source of the bitter taste in this medicinal plant (Yeap et al, 2010;Danladi et al, 2018). Outside of bitter leaf, this medicinal plant is known by a variety of common names in different languages in different regions (for instance, "ebicha" (oromifa) (Bekele and Reddy, 2015), "grawa" (Amharic), and "vernonia tree" (English) (Wubayehu et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Vernonia amygdalina: a comprehensive review of the nutritional makeup, traditional medicinal use, and pharmacology of isolated phytochemicals and compounds

Degu,

Meresa,

Animaw

et al. 2024

Front. Nat. Prod.

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Vernonia amygdalina is a perennial shrub that belongs to the family Asteraceae. The herb is an indigenous African plant that grows in most parts of sub-Saharan Africa. It is probably the most used medicinal plant in the genus Vernonia. Previous studies on the traditional medicinal value, nutritional composition, classes of phytochemical or compound isolation, and evaluation of their pharmacology activity are numerous. This provokes us to review and provide up-to-date evidence-based information on the study plant. A systematic online search using the databases of Google Scholar, PubMed, Science Direct, Wiley, Elsevier and Sci-Hub was carefully applied, using some important key words to get appropriate information. The leafy part of Vernonia amygdalina contributes greatly to the nutritional requirements for human health and to food security since it contains enough concentrations of proximate composition, minerals, and vitamins. The plant parts are used in traditional medicine for many human and animal healthcare purposes, including diarrhea, diabetes, wound healing, tonsillitis, evil eye, retained placenta, headache, eye disease, intestinal parasite, bloating, hepatitis, toothache, anthrax, malaria, urine retention, gastritis, stomach disorders, and snake bites. The chemical analysis revealed the presence of flavonoids, alkaloids, saponins, tannins, triterpenoids, sesquiterpene lactones, steroids, cardiac glycosides, oxalates, phytates, cyanogenic glycosides, and phenols. Additionally, various compounds such as vernolide, luteolin, vernodalol, vernoamyoside A, vernoamyoside B, isorhamnetin, glucuronolactone, and 1-Heneicosenol O-β-D-glucopyranoside were isolated. Some of the isolated compounds pharmacological activity was evaluated against some diseases and showed antioxidant, antibacterial, antifungal, antihelmintic, anticancer, and anti-inflammatory potencies. Thus, the review provides comprehensive information about ethnomedicinal value, nutritional composition, isolated classes of phytochemicals, and compounds, including an evaluation of the pharmacological activity of the isolated compounds of Vernonia amygdalina. A review with this much information could be extremely valuable for future research on developing innovative nutraceutical products.

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Vernonia amygdalina Del: A Mini Review

Cited by 14 publications

References 0 publications

Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19

Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19

Medicinal uses of the Asteraceae family in Zimbabwe: A historical and ecological perspective

Vernonia amygdalina: a comprehensive review of the nutritional makeup, traditional medicinal use, and pharmacology of isolated phytochemicals and compounds

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