Vibrio metschnikovii Bacteremia in a Patient with Cholecystitis

Abstract

Vibrio metschnikovii was isolated from the blood of an 82-year-old patient with peritonitis and an inflamed gallbladder. This is probably the first clinically significant isolate of this new vibrio.

Effects of divalent cations and saccharides on Vibrio metschnikovii cytolysin-induced hemolysis of rabbit erythrocytes

“…Vibrio metschnikovii is widely distributed in the environment (19) and is reported to be associated with disease in animals (4) and humans (15), but direct evidence showing that this organism has pathogenicity has not been established. We have encountered a clinical case of diarrhea caused by this organism and purified the cytolysin produced by the isolate as a possible virulence factor (22).…”

Purification and characterization of Vibrio metschnikovii cytolysin

“…At least 10 Vibrio species have been reported to be associated with human diseases (8,21,22,29,30,35,39). One of these, Vibrio metschnikovii, was first described in 1888 (7) and redefined as a new Vibrio species in 1978 (24).…”

“…In 1981, Jean-Jacques et al (21) described a strain isolated from the blood of an elderly woman with peritonitis and an inflamed gallbladder. It is uncertain whether the organism was the primary pathogen in that case.…”

Current perspectives on the epidemiology and pathogenesis of clinically significant Vibrio spp.

“…metschnikovii. Only one reported case of clinically significant infection attributed to V. metschnikovii has been reported to date, and it involved an 82-year-old diabetic female (83). The patient presented with abdominal pain and cholecystitis, and a blood culture drawn on admission was positive for V. metschnikovii.…”