(<i>Z</i>)-4-(2-Hydroxyanilino)pent-3-en-2-one

Benghanem, Fatiha; Keraghel, Saida; Chahmana, Safia; Ourari, Ali; Lydia, Brelot

doi:10.1107/s1600536812027894

Cited by 3 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ligand of Schiff base 4-(2-Hydroxyaniline) pent-3-en-2-one (2-HyA) was synthesized as shown in Scheme 1. 34,35 By slowly adding an ethanolic solution of (5 mmol) acetylacetone to an ethanolic solution (5 mmol) of 2-aminophenol. The mixture was refluxed with constant stirring for 5 h. then the mixture allowed to cool and the solvent to evaporate slowly overnight.…”

Section: Synthesis Of 4-(2-hydroxyaniline)pent-3-en-2-one (2-hya)mentioning

confidence: 99%

Synthesis of novel chitosan Schiff base and its ZnO nanocomposite for removal of synthetic dye, antimicrobial, and cytotoxicity activity

Gaafar

El‐Taweel

Fouda

et al. 2022

Journal of Bioactive and Compatible Polymers

View full text Add to dashboard Cite

In this work, a novel chitosan Schiff base 4-(2-Hydroxyaniline)pent-3-en-2-one chitosan (2-HyA-CS) and its ZnO nanocomposite (2-HyA-CS/ZnO) were sensitized and characterized by appropriate methods; FTIR, XRD, Elemental analysis, SEM, TEM and TGA. The result of characterization methods confirms the preparation of 2-HyA-CS and 2-HyA-CS/ZnO. The SEM images reveal that chitosan, 2-HyA-CS, and 2-HyA-CS/ZnO have a varied roughness and porous surfaces. The reason for this difference was attributed to the formation of Schiff base 2-HyA-CS and the presence of ZnO nanoparticles in 2-HyA-CS/ZnO. The patterns of XRD and FTIR confirm the formation of 2-HyA-CS and 2-HyA-CS/ZnO. The degree of substitution (DS) of modified chitosan 2-HyA-CS was calculated using Elemental analysis and FTIR.ATR, it was found to be 74%. The adsorption efficiency of the produced adsorbents was compared with pure chitosan to remove of Remazol Brilliant Blue R (RBBR) from an aqueous medium and antimicrobial activity. The removal percentage of RBBR by chitosan, 2-HyA-CS, and 2-HyA-CS/ZnO are 47.12%, 91.9%, and 96.56%, respectively with the following order: 2-HyA-CS/ZnO > 2-HyA-CS > chitosan. Their antimicrobial activities were studied against two Gram negative bacteria ( E. coli and P. aeruginosa), two Gram positive bacteria ( S. aureus and B. cereus) and ( C. albicans) as a yeast strain, the inhibitory zone measurements revealed that the activity of 2-HyA-CS/ZnO is excellent and higher than 2-HyA-CS and pure chitosan. The cytotoxicity of the prepared compound 2-HyA-CS and 2-HyA-CS/ZnO along with pure chitosan was estimated against two human cancer cells MCF-7 cells and HepG-2 cells, the result indicates that 2-HyA-CS/ZnO having higher Inhibitory activity against both MCF-7 and HepG-2 cells with 53.5 ± 2.86 and 27.4 ± 1.23 µg/mL respectively and 2-HyA-CS possessing moderate Inhibitory activity against both MCF-7 and HepG-2 cancer cells with IC50 = 216.5 ± 7.48 and 135.6 ± 6.49 µg/ml respectively.

show abstract

Section: Synthesis Of 4-(2-hydroxyaniline)pent-3-en-2-one (2-hya)mentioning

confidence: 99%

Synthesis of novel chitosan Schiff base and its ZnO nanocomposite for removal of synthetic dye, antimicrobial, and cytotoxicity activity

Gaafar

El‐Taweel

Fouda

et al. 2022

Journal of Bioactive and Compatible Polymers

View full text Add to dashboard Cite

show abstract

A new corrosion inhibitor for steel rebar in concrete: Synthesis, electrochemical and theoretical studies

Bellal

Benghanem

Keraghel

2021

Journal of Molecular Structure

View full text Add to dashboard Cite

Crystal structure of 4-bromo-2-(1H-imidazo[4,5-b]pyridin-2-yl)phenol

Ouari

2015

Acta Cryst E

View full text Add to dashboard Cite

In the title compound, C12H8BrN3O, the 4-bromophenol ring is coplanar with the planar imidazo[4,5-b]pyridine moiety (r.m.s deviation = 0.015 Å), making a dihedral angle of 1.8 (2)°. There is an intramolecular O—H⋯N hydrogen bond forming an S(6) ring motif. In the crystal, molecules are linked via N—H⋯N and O—H⋯Br hydrogen bonds, forming undulating sheets parallel to (10-2). The sheets are linked by π–π interactions [inter-centroid distance = 3.7680 (17) Å], involving inversion-related molecules, forming a three-dimensional structure.

show abstract

(Z)-4-(2-Hydroxyanilino)pent-3-en-2-one

Cited by 3 publications

References 20 publications

Synthesis of novel chitosan Schiff base and its ZnO nanocomposite for removal of synthetic dye, antimicrobial, and cytotoxicity activity

Synthesis of novel chitosan Schiff base and its ZnO nanocomposite for removal of synthetic dye, antimicrobial, and cytotoxicity activity

A new corrosion inhibitor for steel rebar in concrete: Synthesis, electrochemical and theoretical studies

Crystal structure of 4-bromo-2-(1H-imidazo[4,5-b]pyridin-2-yl)phenol

Contact Info

Product

Resources

About