2024
DOI: 10.7717/peerj.18560
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β-Defensin versus conventional markers of inflammation in periprosthetic joint infection: a retrospective study

Javier Fernández-Torres,
Yessica Zamudio-Cuevas,
Karina Martínez-Flores
et al.

Abstract: Background Diagnosing periprosthetic joint infection (PJI) remains a significant challenge for healthcare professionals. Commonly utilized inflammatory markers include erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and white blood cells (WBC). Human β-defensin 1 (β-defensin) is an antimicrobial peptide elevated in infection, yet its diagnostic value for PJI has not been explored. The purpose of this study was to evaluate the efficacy of synovial β-defensin as a diagnostic marker… Show more

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