IAEA biological reference materials

Preparation and analysis of a frozen mussel tissue reference material for the determination of trace organic constituents

“…As shown in Table I, there is generally good agreement between the LC-FL and GC-MS determinations. Differences in the mean values for the two techniques were 1-4% for phenanthrene, anthracene, perylene, and benzo[g/u] perylene; 12% for fluoranthene and pyrene; and 13-15% for benzo[o]pyrene, benzo [5]fluoranthene, and indeno[l,2,3-cd]pyrene. Based on the results from these two techniques, certified concentrations of these nine PAHs were determined and are summarized in Table I.…”

“…Several of the PCB congeners listed in Table III coelute with each other in the commonly used GC-ECD analysis on a DB-5 or similar column (29). For the 13 PCB congeners listed in Table III, 5 congeners may have some contribution from coeluting congeners, e.g., PCB 15 with PCB 18, PCB 95 with PCB 66, PCB 90 with PCB 101, PCB 164 and PCB 163 with PCB 138, and PCB 159 and PCB 182 with PCB 187 (see Figure 2). The extent of the contribution of the coeluting congeners has been shown to vary in marine samples (31).…”

“…Mussel tissue reference materials for trace element determinations are available from several sources including the following: the National Institute of Environmental Studies (NIES; Tsukuba, Japan), the Community Bureau of Reference (BCR; Brussels, Belgium), and the International Atomic Energy Agency (IAEA; Vienna, Austria) f Permanent address: Department of Analytical and Environmental Chemistry, University of Ulm, 7900 Ulm, Federal Republic of Germany. (3)(4)(5)(6)(7). The Marine Analytical Chemistry Standards Program of the National Research Council Canada (NRCC) has produced several biological tissue materials certified for trace element content including lobster hepatopancreas, dogfish liver, and dogfish muscle (8,9).…”

“…Liquid-liquid extraction, (1) coprecipitation, (2) chelating ion exchange, (3) solvent evaporation, (4) hydride generation, (5) and chelation-solvent extraction (6-10) have been used for preconcentration.…”

Reviews of Environmental Contamination and Toxicology

“…In addition to significant advancement in nail analysis, an improved quality assurance, which is essential, depends on employment of proper certified reference materials (CRM) and participation in the interlaboratory quality control programme (M' Baku and Parr 1982;Parr et al 1988). Currently, the reference material for toenails is available from National Institute of Standard and Technology (USA) and can be used to ensure the validity of adopted methods.…”