2015
DOI: 10.1007/s11420-014-9409-5
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Iatrogenic Contributions to Cervical Adjacent Segment Pathology

Abstract: Background: Anterior cervical discectomy and fusion (ACDF) is widely accepted as a predictably excellent procedure. On the other hand, adjacent level pathology following ACDF is a well-known phenomenon which undercuts surgical outcome. However, the extent to which ACDF accelerates this phenomenon in the naturally degenerating cervical spine is still to be understood. Questions/Purposes: To summarize the current evidence concerning adjacent segment pathology in the light of biomechanics, natural history, postop… Show more

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Cited by 7 publications
(2 citation statements)
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“…According to whether there are clinical symptoms, ASD can be classified into adjacent segment degeneration and adjacent segment disease. Adjacent segment degeneration is defined as imaging degeneration of adjacent segments without clinical symptoms after fusion, whereas adjacent segment disease exhibits new symptoms corresponding to imaging changes of adjacent segments in the fusion area [ 13 , 14 ]. The ASD was not subdivided in this study.…”
Section: Methodsmentioning
confidence: 99%
“…According to whether there are clinical symptoms, ASD can be classified into adjacent segment degeneration and adjacent segment disease. Adjacent segment degeneration is defined as imaging degeneration of adjacent segments without clinical symptoms after fusion, whereas adjacent segment disease exhibits new symptoms corresponding to imaging changes of adjacent segments in the fusion area [ 13 , 14 ]. The ASD was not subdivided in this study.…”
Section: Methodsmentioning
confidence: 99%
“…According to these clinical observations, the discrepancy in incidence between radiographic and symptomatic ASDs is an indisputable fact. However, it is still unknown if radiographic degeneration can be a precursor for symptomatic spondylosis [ 47 ]. The etiology of ASD is multifactorial and depends on (1) the natural history of the adjacent disc, (2) biomechanical stress on the adjacent level caused by the fusion, and (3) anatomical disruption at the adjacent level during the initial surgery [ 48 49 50 ].…”
Section: Controversial Issuesmentioning
confidence: 99%