Iatrogenic damage in the neonatal period

Nikkels, Peter G. J.

doi:10.1016/j.siny.2004.01.002

Cited by 4 publications

(2 citation statements)

References 33 publications

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“…In our study, 29 adverse clinical practice issues, categorised into errors of diagnosis and management (including iatrogenic injury), would have been overlooked if an autopsy had not been performed. The identification of these types of errors, which can be reduced as part of an audit cycle, is a very valuable function of autopsy, especially in the case of perinatal death where the patient cannot report injury [12,17] .…”

Section: Value Of Post-mortem Examinationmentioning

confidence: 99%

The Value of Neonatal Autopsy

et al. 2011

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Background and Objective: Neonatal autopsy rates were in decline internationally at the end of the last century. Our objective was to assess the current value of neonatal autopsy in providing additional information to families and healthcare professionals. Methods: We conducted a review of neonatal autopsies performed in a tertiary perinatal centre over an 11-year period. Primary outcomes measured were the annual neonatal autopsy rates and concordance rates between clinical and autopsy diagnoses of the primary cause of death. Secondary outcomes were the clinical, genetic and audit value of the examinations. Findings were used to inform the consent process, and the effect this had on institutional post-mortem rates was assessed over the subsequent 5-year period. Results: There was a marked decline in the annual neonatal autopsy rate from 73% in 1994 to 48% in 2004. 164 cases met the inclusion criteria for review. Complete concordance for cause of death was reached in 91% of cases. Previously unsuspected or unconfirmed clinical conditions, other than the primary cause of death, were uncovered at autopsy in 85 cases. Detailed information on inheritable conditions was obtained in 45 cases. Findings with perceived ‘audit value’ for clinical practice were identified in 29 cases. The dissemination of this information to staff and families contributed to the stabilisation of the consent rate in the following 5-year period. Conclusion: Neonatal autopsy remains a valuable diagnostic tool as it provides critical clinical and audit information for healthcare professionals and families.

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Section: Value Of Post-mortem Examinationmentioning

confidence: 99%

The Value of Neonatal Autopsy

et al. 2011

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“…A survey of comprehensive investigations of dermatologic manifestations in preterms is lacking in the literature. The majority of the review articles summarize and describe the etiology of typical iatrogenic skin injuries in NICUs (e.g., thermal burns, chemical burns, light burns, scalp injuries, extravasation injuries, pressure ulcers, epidermal stripping) . Most of the articles available have reported on special skin injuries (e.g., extravasation injuries, pressure ulcers, burns).…”

Section: Discussionmentioning

confidence: 99%

Overview of Dermatologic Disorders of Neonates in a Central Regional Intensive Care Unit in Hungary

Csoma

Meszes

Mader

et al. 2014

Pediatric Dermatology

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The immaturity and vulnerability of the skin and epidermal barrier function and the frequent iatrogenic complications following diagnostic and therapeutic procedures are often associated with skin manifestations in infants in neonatal intensive care units (NICUs). The aim of the current study was to investigate dermatologic disorders in neonates in our NICU. A prospective cohort study was conducted in the NICU at the Department of Pediatrics at the University of Szeged between January 2012 and January 2013. All full- and preterm infants hospitalized in the NICU underwent whole-body skin examinations and all dermatologic disorders and treatment modalities were recorded. Eighty-nine dermatologic conditions were detected in 64 of the 211 neonates admitted to the NICU. A wide variety of clinical symptoms accompanied these conditions in these preterm and severely ill full-term infants. A considerable proportion of the disorders that were seen resulted from the immaturity of the skin and various iatrogenic complications. Dermatologic disorders are frequent in neonates requiring intensive care. Prevention, early detection, and optimal treatment of these disorders with modern, standardized skin care management strategies can result in significant improvements in barrier function and in the integrity of the skin, increasing the overall efficacy of neonatal intensive care.

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