Cosmogenic 3 He, 2 6 A1, and 10 Be have been measured in a variety of Antarctic glacial deposits in the McMurdo Sound-Dry Valleys region. The goals of this project were to provide age constraints for Antarctic glacial events, to investigate production mechanisms of 3 He, 10Be, and 2 6 A1 in terrestrial rocks, to constrain the importance of loss of 3 He from quartz due to diffusion, and to refine methods of exposure-age dating.Moraines deposited in Arena Valley by the Taylor Glacier, an outlet glacier of the East Antarctic Ice Sheet, have exposure ages from -120 kyr to 2 myr. 1 0 Be and 3 He ages of 122 + 29 and 134 ± 54 kyr, respectively, for the Taylor II moraine are consistent with deposition during isotope stage 5e (-120 kyr) and with aerial expansions of the East Antarctic Ice Sheet during interglacial periods. Mean 1 0 Be exposure ages for older moraines in the valley are 362 + 26 kyr (Taylor III), 1.1 ± 0.1 myr (Taylor IVa) and 1.9 ± 0.1 myr (Taylor IVb). Because these older moraines were deposited at most -200 m above the Taylor II limit their ages suggest that major ice sheet advances during the last 2 myr have been broadly similar in magnitude to changes during the last glacial-interglacial cycle. 10 Be ages for stratigraphically older drift deposited by the Taylor Glacier allow extension of this conclusion to -3 myr.1 0 Be measurements in high altitude, pre-Pleistocene glacial deposits in the Dry Valleys preclude rapid uplift of the Transantarctic Mountains (400-1000 m/myr) suggested by controversial biostratigraphic studies of Sirius Group tills. Comparison of measured 10Be concentrations in Sirius Group deposits with those predicted with a model of the effects of uplift on 1 0 Be production suggests minimal uplift of the Transantarctic Mountains over the last 3 myr.3 He, 1 0 Be and 2 6 A1 ages for the "late Wisconsin" Ross Sea Drift, a glacial drift deposited on the coast of McMurdo Sound by the Ross Sea Ice Sheet, range from 8-106 kyr. The age range suggests that this deposit does not, as previous studies suggested, represent a single ice advance in response to lowered sea level at the last glacial maximum. The age range may reflect several ice sheet advances during the last glacial period.Paired measurements of 3 He and 1 0 Be in a number of quartz sandstones from the Dry Valleys region show that cosmogenic 3 He is not completely retained on time scales of greater than 200 kyr. The 3 He and 1 0 Be data, combined with measurements of 3 He concentrations in quartz as a function of grain size, suggest effective 3 He diffusion coefficients in quartz from ~10 -19 to 10-17 cm 2 s -1. These values are one to three orders of magnitude greater than previous experimental determinations extrapolated to low temperature. The data also suggest that 3 He diffusion rates in quartz do not follow simple volume diffusion trends and are probably sample dependent.Crushing quartz grains in vacuo releases variable concentrations of 3 He and 4 He and releases helium with surprisingly high isotopic compositions, u...