2021
DOI: 10.1001/jamadermatol.2021.3498
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Ichthyosiform Rashes and Joint Pain in a Boy

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Cited by 2 publications
(4 citation statements)
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“…In addition to POTASH, some of the other potential etiologies for a positive fist sign include compartment syndrome, congenital conditions (such as Blau syndrome), endocrine disorders (such as acromegaly), giant lipoma (with associated carpal tunnel syndrome), intravenous drug use (with puffy hand syndrome), and rheumatologic diseases (such as remitting seronegative symmetrical synovitis with pitting edema). 1 , 6 , 7 , 8 , 9 , 10…”
Section: Discussionmentioning
confidence: 99%
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“…In addition to POTASH, some of the other potential etiologies for a positive fist sign include compartment syndrome, congenital conditions (such as Blau syndrome), endocrine disorders (such as acromegaly), giant lipoma (with associated carpal tunnel syndrome), intravenous drug use (with puffy hand syndrome), and rheumatologic diseases (such as remitting seronegative symmetrical synovitis with pitting edema). 1 , 6 , 7 , 8 , 9 , 10…”
Section: Discussionmentioning
confidence: 99%
“… 2 , 3 , 4 , 5 Other causes of a positive fist sign include fibrosis, hemorrhage, infection, lymphatic obstruction, overgrowth of bone and soft tissue, space occupying lesion with nerve compression, and trauma. 1 , 6 , 7 , 8 , 9 , 10 Depending on the etiology, the inability to make a fist will persist or may resolve either spontaneously, after corticosteroid treatment, or post-surgery. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10…”
Section: Discussionmentioning
confidence: 99%
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“…Similar to the patient in this letter, both of the investigators of the prior papers on POTASH recognized the inability of the affected individuals to make a fist; this is referred to as a positive fist sign [10,11]. In addition to POTASH, a positive fist sign has also been observed in individuals with acromegaly, Blau syndrome, carpal tunnel syndrome (associated with giant lipoma), compartment syndrome, puffy hand syndrome, and remitting seronegative symmetrical synovitis with pitting edema [1][2][3]5,7,13]. Various mechanisms have been associated with the development of a positive fist sign; in patients with POTASH, edema-which subsequently resolves spontaneously resulting in the patient regaining their ability to clench the fingers into a tight fist (and thereby demonstrating a negative fist sign)-has been suggested as the etiology [10].…”
Section: Ravaglia Et Al Observed Post Ambulatory Handmentioning
confidence: 99%