Identification and antimicrobial activity of the sesquiterpene lactone mixture extracted from Smallanthus sonchifolius dried leaves

Andrade, Eriel Forville de; Carpiné, Danielle; Dagostin, João Luiz Andreotti; Barison, Andersson; Rüdiger, André Luis; Muñiz, Graciela Inés Bolzón de; Masson, Maria Lúcia

doi:10.1007/s00217-017-2918-y

Cited by 12 publications

(7 citation statements)

References 28 publications

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“…In the case of this species, only water extracts had a statistically significant effect on this growth parameter. Differences in the sensitivity of Gram-positive and Gram-negative strains may be due to the different mechanism of action of polyphenols and sesquiterpene lactones on the cell wall, attributable to the polar groups of these compounds [ 44 , 45 ]. Additionally, the presence of an α-methylene-γ-lactone group attached to the SL molecule may act as Michael-type acceptor of biological nucleophiles [ 45 ].…”

Section: Resultsmentioning

confidence: 99%

Novel Biodegradable Starch Film for Food Packaging with Antimicrobial Chicory Root Extract and Phytic Acid as a Cross-Linking Agent

Jaśkiewicz

Budryn

Nowak

et al. 2020

Foods

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The aim of the study was to obtain and evaluate the properties of biodegradable starch film with the addition of phytic acid (0.05%) as a cross-linking agent and chicory root extract (1–5%) as an antimicrobial agent. To prepare biodegradable film, extracts from chicory root obtained with water or methanol were used. The content of bioactive compounds (sesquiterpene lactones and total polyphenols) was evaluated in chicory extracts. The antibacterial activity of the extracts was tested against Gram-negative bacteria (Pseudomonas fluorescens, Escherichia coli) and Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus) using the microculture method. The extracts acted as bacteriostatic agents, decreasing the growth rate (µmax), and extending the lag phase (tlag). The most sensitive bacterium in terms of film bacteriostatic activity was P. fluorescens; all extracts, irrespective of the solvent used, decreased its µmax value. S. aureus was the least sensitive. The obtained films were tested for their properties as food packaging (color, thickness, permeability, mechanical strength). Phytic acid improved the tensile strength and barrier properties of the films. The antimicrobial activity of the films was studied by the disk diffusion method against Gram-negative (P. fluorescens, E. coli) and Gram-positive (B. subtilis, S. aureus) bacteria, as well as fungi (Candida albicans, Aspergillus niger). The growth-inhibiting activity of each obtained film was observed for all tested microorganisms, and the most beneficial effect was observed for films with the 5% level of added extracts obtained with water. The growth-inhibiting activity for fungi, in particular for the yeast C. albicans, was low.

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Section: Resultsmentioning

confidence: 99%

Novel Biodegradable Starch Film for Food Packaging with Antimicrobial Chicory Root Extract and Phytic Acid as a Cross-Linking Agent

Jaśkiewicz

Budryn

Nowak

et al. 2020

Foods

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“…The antimicrobial activity of sage extracts was deter-mined using the disc diffusion method [24] against Staphylococcus aureus ATCC 29213, Escherichia coli ATCC 25922, Salmonella…”

Section: Antimicrobial Activity Of Sage Extractsmentioning

confidence: 99%

Effect of the different infrared levels on some properties of sage leaves

Kayacan

Atık

Akman

et al. 2023

CI&CEQ

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This study aims to investigate the effect of different infrared powers (IP) (38, 50, 62, 74, and 88 W) on drying kinetics, total phenolic content (TPC) and individual phenolics, antioxidant activity (AA) and antibacterial activity, and color quality of sage leaves. IP level significantly affected (p<0.05) drying kinetics and bioactive contents and color quality of sage leaves. Higher TPC and AA were obtained from the sample dried at 88 W. Rosmarinic acid, caffeic acid, gallic acid, and luteolin were found as major phenolic compounds and their higher levels were obtained from the samples dried at IP level of 88 W. All samples showed antibacterial activity on test pathogens. A higher correlation was observed between TPC, rosmarinic acid level, and antibacterial activity (P>0.80). This study suggested that sage leaves should be dried at 88 W regarding lower drying times and color changes, lower phenolic degradation, and higher antibacterial activity.

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“…The only microorganism susceptible to this mixture was S. aureus (ATCC 29213), and the MIC value was 750 μg/mL. The authors state that its activity might be related to its lipophilicity and weak polarity [ 26 ]. Costunolide and eremanthin isolated from Costus speciosus were not active against bacteria, although they proved satisfactory antifungal activity against Trichophyton mentagrophytes, Trichophyton simii, Trichophyton rubrum 296, Trichophyton rubrum 57, Aspergillus niger, Epidermophyton floccosum, Curvularia lunata, Magnaporthe grisea , and the MIC value were ranging from 31.25 to 250 μg/mL [ 27 ].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Biological Activity of Selected Natural and Synthetic Terpenoid Lactones

Surowiak

Balcerzak

Lochyński

et al. 2021

IJMS

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Terpenoids with lactone moieties have been indicated to possess high bioactivity. Certain terpenoid lactones exist in nature, in plants and animals, but they can also be obtained by chemical synthesis. Terpenoids possessing lactone moieties are known for their cytotoxic, anti-inflammatory, antimicrobial, anticancer, and antimalarial activities. Moreover, one terpenoid lactone, artemisinin, is used as a drug against malaria. Because of these abilities, there is constant interest in new terpenoid lactones that are both isolated and synthesized, and their biological activities have been verified. In some cases, the activity of the terpenoid lactone is specifically connected to the lactone moiety. Recent works have revealed that new terpenoid lactones can demonstrate such functions and are thus considered to be potential active agents against many diseases.

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Identification and antimicrobial activity of the sesquiterpene lactone mixture extracted from Smallanthus sonchifolius dried leaves

Cited by 12 publications

References 28 publications

Novel Biodegradable Starch Film for Food Packaging with Antimicrobial Chicory Root Extract and Phytic Acid as a Cross-Linking Agent

Novel Biodegradable Starch Film for Food Packaging with Antimicrobial Chicory Root Extract and Phytic Acid as a Cross-Linking Agent

Effect of the different infrared levels on some properties of sage leaves

Biological Activity of Selected Natural and Synthetic Terpenoid Lactones

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