Identification and characterization of novel single nucleotide polymorphism markers for fat deposition in muscle tissue of pigs using amplified fragment length polymorphism

Supakankul, Pantaporn; Kumchoo, Tanavadee; Mekchay, Supamit

doi:10.5713/ajas.16.0200

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…At the gene level, some molecules known to be related to FE were differentially abundant between FE-divergent pigs. For jejunum, these comprise, for instance, acid phosphatase 2 (ACP2; high FE Ͻ low FE), arginase 2 (ARG2; high FE Ͻ low FE), fibrillin 1 (FBN1; high FE Ͼ low FE), and guanylate cyclase 1 soluble subunit beta (GUCY1B3; high FE Ͼ low FE), which have been proposed as candidate genes for FE-related traits like average daily gain and back fat in livestock (13,14,55,59). Moreover, GUCY1B3 and lipase H (LIPH; high FE Ͻ low FE) were previously found to be differentially expressed in small intestine samples related to the intestinal development (44) and in the context of divergent feed intake (36), respectively.…”

Section: Resultsmentioning

confidence: 99%

Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients

Reyer

Oster

Magowan

et al. 2018

Physiological Genomics

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Feed efficiency (FE) is a measure of the rate between feed intake and body weight gain and is subject to constant progress in pigs, based on extensive performance tests and analyses of physiological parameters. However, endocrine regulatory circuits that comprise the sensation and perception of intrinsic requirements and appropriate systemic responses have not yet been fully elucidated. It is hypothesized that the gut-brain axis, which is a network of hierarchical anterior regulatory tissues, contributes largely to variations in FE. Therefore, full-sib pigs with extreme residual feed intake values were assigned to experimental groups of high and low FE. Relevant hormones, minerals, and metabolites including fatty acid profiles were analyzed in serum to assess postprandial conditions. Transcriptome profiles were deduced from intestinal (duodenum, jejunum, ileum) and neuroendocrine tissues (hypothalamus). Serum analyses of feed-efficient animals showed an increased content of the incretin GIP, calcium, magnesium, β-hydroxybutyric acid, and fat compared with low-FE pigs. Complementary expression profiles in intestinal tissues indicate a modulated permeability and host-microbe interaction in FE-divergent pigs. Transcriptomic analyses of the hypothalamus showed that differences between the FE groups in appetite and satiety regulation are less pronounced. However, hypothalamic abundance of transcripts like ADCY7, LHCGR, and SLC2A7 and molecular signatures in local and systemic tissue sites indicate that increased allocation and circulation of energy equivalents, minerals, and hormones are promoted in feed-efficient animals. Overall, patterns of gastrointestinal hormones and gene expression profiles identified host-microbiota interaction, intestinal permeability, feed intake regulation, and energy expenditure as potential mechanisms affecting FE in pigs.

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Section: Resultsmentioning

confidence: 99%

Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients

Reyer

Oster

Magowan

et al. 2018

Physiological Genomics

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“…If scientists require black-bone chicken samples for the purposes of breeding or the study of genetics, they should select chickens who display a black color in most of their organs. Notably, some studies require that samples should possess extreme differences between two phenotypes [28]. This means that we need to include black-bone chickens that have mostly black colored organs in future research studies focusing on genetic selection or breeding.…”

mentioning

confidence: 99%

Distribution of Melanin Pigmentation in 33 Organs of Thai Black-Bone Chickens (Gallus gallus domesticus)

Nganvongpanit

Kaewkumpai

Kochagul

et al. 2020

Animals

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The black-bone chicken (Gallus gallus domesticus) is a breed of chicken that is commonly found in Thailand. This breed is known for having a number of black colored organs. Consumers have been notably attracted to the black-bone chicken breed for the characteristic darkness that is observed in many of its organs. However, the degree of darkness in all organs of the black-bone chicken is still in question. Importantly, there have not yet been any published reports on the distribution of melanin pigment in the organs of the black-bone chicken. This research study aims to examine the distribution of the melanin pigment in 33 organs of the Thai black-bone chicken. Ten black-bone chickens (five male, five female) were included in this study. Thirty-two organs including the brain, spinal cord, sciatic nerve, larynx, trachea, syrinx, lungs, heart, pericardium, aorta, brachial vein, kidney, cloaca, oviduct, testis, gastrocnemius muscle, femur, tongue, esophagus, crop, proventriculus, gizzard, duodenum, jejunum, ileum, cecum, pancreas, liver, gall bladder, omentum, abdominal fat, spleen, and skin were examined in this study. Histological sections taken from tissue samples of each of these organs were studied. The findings revealed that the presence of the melanin pigment was not significantly different (p > 0.005) between male and female specimens. Notably, the liver was the only organ in which the melanin pigment had not accumulated. Consequently, there was not a uniform pattern of melanin pigment accumulation throughout the organs of the chickens. The melanin pigment was present in all of the tissue layers of most organs, while the melanin pigment was found in only specific layers of some of the organs. In conclusion, the distribution of melanin pigmentation in the organs of each of the animals in this study was found to be different. However, in some tissue samples, such as those obtained from the liver, no accumulation of the melanin pigment was observed.

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Identification and characterization of novel single nucleotide polymorphism markers for fat deposition in muscle tissue of pigs using amplified fragment length polymorphism

Cited by 2 publications

References 29 publications

Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients

Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients

Distribution of Melanin Pigmentation in 33 Organs of Thai Black-Bone Chickens (Gallus gallus domesticus)

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