2024
DOI: 10.20944/preprints202402.1767.v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Identification and Diagnosis of Complete Haptoglobin Gene Deletion, the Gene Responsible for Adverse Posttransfusion Reactions

Mikiko Soejima,
Yoshiro Koda

Abstract: Allergic reactions are the most frequent adverse effects of blood transfusion, and anaphylactic shock, although less frequent, is systemic and serious. The causes of allergic reactions to blood transfusions are largely unknown, but deficiencies in serum proteins such as haptoglobin (Hp) can lead to anaphylactic shock. A complete deletion of the haptoglobin gene (HPdel) was first identified in families with anomalous inheritance and then verified as a genetic variant that can cause anaphylactic shock because ho… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 60 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?