Identification and localization of genetic material of African swine fever virus by autoradiography

Vigário, J. D.; Relvas, Marta; Ferraz, F.P.; Ribeiro, Jhonatan M; Pereira, Claiton Gonçalves

doi:10.1016/0042-6822(67)90108-0

Cited by 19 publications

(9 citation statements)

References 7 publications

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“…ASFV DNA replication has two phases, an early phase in the cell nucleus and a later prominent phase within the virus factories (Brookes et al 1998;Garcia-Beato et al 1992;Moulton and Coggins 1968b;Oura et al 1998b;Pan et al 1980;Rojo et al 1999;Tabares and Sanchez Botija 1979;Vigario et al 1967). Notably and consistent with a role for the nucleus in DNA replication, ASFV growth was markedly inhibited in enucleated Vero cells (Ortin and Viñuela 1977).…”

Section: Viral Dna Replicationmentioning

confidence: 76%

African Swine Fever Virus

Tulman

Delhon

et al. 2009

Current Topics in Microbiology and Immunology

134

117

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African swine fever virus (ASFV) is a large, intracytoplasmicallyreplicating DNA arbovirus and the sole member of the family Asfarviridae . It is the etiologic agent of a highly lethal hemorrhagic disease of domestic swine and therefore extensively studied to elucidate the structures, genes, and mechanisms affecting viral replication in the host, virus-host interactions, and viral virulence. Increasingly apparent is the complexity with which ASFV replicates and interacts with the host cell during infection. ASFV encodes novel genes

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Section: Viral Dna Replicationmentioning

confidence: 76%

African Swine Fever Virus

Tulman

Delhon

et al. 2009

Current Topics in Microbiology and Immunology

134

117

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“…Sera from swine inoculated with attenuated strains followed by a challenge with the homologous virulent virus shouted a good capacity to react with ASFV antigens in complement fixation, agar gel diffusion, immunofluorescent and hemadsorption inhibition (HADI) tests (6,10,13,14,15).…”

Section: Introductionmentioning

confidence: 99%

Antigenic relationships among strains of African swine fever virus

Vigário

Terrinha

Nunes

1974

Archiv f Virusforschung

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Cross-reaction in hemadsorption inhibition tests with African swine fever viruses and swine immune sera permitted the separation of two antigenic subgroups, A and B. However, there are African swine fever viruses which cannot be included in these subgroups, thus constituting at least one third subgroup. Nonhemadsorbing African swine fever viruses are described which were isolated from pigs dying with chronicM lesions of pneumonia as shown by autopsy; several hypotheses to explain the appearance of these nonhemadsorbing strains are advanced. Electron microscopy studies suggest that the subgroup-specific antigen is associated with the outer structural component of the virion, which derives from the cytoplasmic membrane of the infected cell.

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“…Replication of ASFV, including DNA synthesis (Vigario et al, 1967 ;Moulton & Coggins, 1968 ;Pan et al, 1980 ;Garcia-Beato et al, 1992) and particle assembly, is associated with perinuclear inclusions known as ' virus factories' (Moura-Nunes et al, 1975). The virus factory contains membrane elements of endoplasmic reticulum (ER) origin and virus particles at various stages of assembly (Moura-Nunes et al, 1975 ;Brookes et al, 1996 ;Rouiller et al, 1998).…”

Section: Introductionmentioning

confidence: 99%