2022
DOI: 10.21203/rs.3.rs-1422386/v1
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Identification of a 5-Gene-Based Signature to Predict Prognosis and Correlate Immunomodulators for Rectal Cancer

Abstract: Background Specific tumour markers that are similar to the 21-gene assay in breast cancer, have yet to be identified in rectal cancer. The objective of this study is to identify a novel genetic signature in rectal cancer to help predict survival and provide clues for immunotherapy. Methods Differentially Expressed Genes were obtained from two GEO datasets of rectal cancer. By using data from TCGA and GSE133057, two cohorts of rectal cancer were applied to establish and evaluate the prognostic signature. Then… Show more

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