Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo–keto reductase 1C33 by site-directed mutagenesis

Endo, Shunsuke; Matsunaga, Toshiyuki; Ikari, Akira; El‐Kabbani, Ossama; Hara, Akira; Kitade, Yukio

doi:10.1016/j.abb.2015.01.026

Archives of Biochemistry and Biophysics

2015

DOI: 10.1016/j.abb.2015.01.026

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Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo–keto reductase 1C33 by site-directed mutagenesis

Shunsuke Endo

Toshiyuki Matsunaga

Akira Ikari

et al.

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Identification of a determinant for strict NADP(H)-specificity and high sensitivity to mixed-type steroid inhibitor of rabbit aldo–keto reductase 1C33 by site-directed mutagenesis

Cited by 1 publication

References 46 publications

Engineering aldo-keto reductase 1B10 to mimic the distinct 1B15 topology and specificity towards inhibitors and substrates, including retinoids and steroids

Engineering aldo-keto reductase 1B10 to mimic the distinct 1B15 topology and specificity towards inhibitors and substrates, including retinoids and steroids

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