Identification of a mutagenic chlorination by-product produced from (E)-1, 3-dichloropropene (a component of nematocide DD) by using high resolution LC/MS and multivariate analysis

Palladium-Catalyzed Nitrile-Assisted C(sp3)–Cl Bond Formation for Synthesis of Dichlorides

“…Chlorine-containing organic molecules exist ubiquitously in natural products, pharmaceuticals, agricultural chemicals, and functional materials . For example, the reported data show that over 2000 chlorine-containing compounds have been found in natural products, and many of them display significant antibiotic or cytotoxic properties .…”