Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe

Rubbenstroth, Dennis; Peus, Elisabeth; Schramm, Eva; Kottmann, Daniel; Bartels, Hilke; McCowan, Christina; Schulze, Christoph; Akimkin, Valerij; Fischer, Nicole; Wylezich, Claudia; Hlinak, Andreas; Spadinger, Anja; Großmann, Ernst; Petersen, Henning; Grundhoff, Adam; Rautenschlein, Silke; Teske, Lydia

doi:10.1111/tbed.13065

Cited by 26 publications

(106 citation statements)

References 36 publications

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“…There was a conspicuous correlation with prior attendance of shows. The prevalence of pigeon RVA among clinically affected pigeon lofts turned out to be much lower than in other studies [4,5]. Most of the analysed samples from the pigeon lofts were sent months after the first symptoms occurred.…”

Section: Discussionmentioning

confidence: 54%

“…The VP6 genes of these RVA strains showed a high level of nucleotide sequence identity to each other, ranging between 99% and 100%. The analysis of partial VP6 gene sequences (519 nt) from the pigeon RVA detected in this study revealed that these isolates clustered with genotype I4 [4] (Fig. 2).…”

Section: Resultsmentioning

confidence: 68%

“…Most of the lofts included in this study reported clinical signs like those associated with pigeon RVA infection [4] and YPDS [8]. There was a conspicuous correlation with prior attendance of shows.…”

Section: Discussionmentioning

confidence: 64%

“…Most of the analysed samples from the pigeon lofts were sent months after the first symptoms occurred. It has been observed that pigeon RVA can be shed for three months after infection [4]. It is therefore conceivable that RVA may have been circulating in the loft at the time when clinical signs were apparent but was no longer excreted at the time of sample collection.…”

Section: Discussionmentioning

confidence: 99%

“…Infections are usually restricted to the gastrointestinal tract and are self-limiting, although fatalities can occur as a result of dehydration, especially in younger animals. In contrast, the newly described pigeon-associated clade of rotavirus A (RVA) has been shown to cause systemic infections [4], resulting in clinical signs such as apathy, fluffy plumage, inappetence, emesis, stowed crop, emaciation, and diarrhoea [1,4,5]. So far, viruses of this clade have only been detected in pigeons.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of pigeon rotavirus infections: animal exhibitions as a risk factor for pigeon flocks

et al. 2020

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A total of 289 cloacal swabs from pigeons from 29 different breeders in Germany were collected. In addition, samples from pigeons exhibited at shows were collected. The detailed health status of the pigeon flocks was recorded. Samples were analysed for the presence of the recently discovered pigeon rotavirus and pigeon circovirus. Pigeon rotavirus was found in 10.3% and pigeon circoviruses was found in 65.5% of sampled pigeon lofts. The study revealed a strong relationship between the attendance of shows and the occurrence of different clinical signs. The higher prevalence of pigeon rotavirus in exhibited animals indicates that exhibitions are a risk factor for the transmission of this pathogen.

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Section: Discussionmentioning

confidence: 54%

Section: Resultsmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence of pigeon rotavirus infections: animal exhibitions as a risk factor for pigeon flocks

et al. 2020

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Untargeted metagenomics shows a reliable performance for synchronous detection of parasites

et al. 2020

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Shotgun metagenomics with high-throughput sequencing (HTS) techniques is increasingly used for pathogen identification and characterization. While many studies apply targeted amplicon sequencing, here we used untargeted metagenomics to simultaneously identify protists and helminths in pre-diagnosed faecal and tissue samples. The approach starts from RNA and operates without an amplification step, therefore allowing the detection of all eukaryotes, including pathogens, since it circumvents the bias typically observed in amplicon-based HTS approaches. The generated metagenomics datasets were analysed using the RIEMS tool for initial taxonomic read assignment. Mapping analyses against ribosomal reference sequences were subsequently applied to extract 18S rRNA sequences abundantly present in the sequence datasets. The original diagnosis, which was based on microscopy and/or PCR, could be confirmed in nearly all cases using ribosomal RNA metagenomics. In addition to the prediagnosed taxa, we detected other intestinal eukaryotic parasites of uncertain pathogenicity (of the genera Dientamoeba, Entamoeba, Endolimax, Hymenolepis) that are often excluded from routine diagnostic protocols. The study clearly demonstrates the applicability of untargeted RNA metagenomics for the parallel detection of parasites.

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Rotavirus A and D circulating in commercial chicken flocks in southeastern Brazil

Dias,

Pinheiro,

Petrucci

et al. 2023

Vet Res Commun

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Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe

Cited by 26 publications

References 36 publications

Prevalence of pigeon rotavirus infections: animal exhibitions as a risk factor for pigeon flocks

Prevalence of pigeon rotavirus infections: animal exhibitions as a risk factor for pigeon flocks

Untargeted metagenomics shows a reliable performance for synchronous detection of parasites

Rotavirus A and D circulating in commercial chicken flocks in southeastern Brazil

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