Identification of a Novel Papillomavirus Type (MfoiPV1) Associated with Acrochordon in a Stone Marten (Martes foina)

Abstract

Papillomaviruses (PVs) are an extremely large group of viruses that cause skin and mucosal infections in humans and various domestic and wild animals. Nevertheless, there is limited knowledge about PVs in wildlife hosts, including mustelid species. This study describes a case in stone marten (Martes foina) with a clinical manifestation of skin tumor, which is rather atypical for infections with PVs. The result of the papillomavirus PCR performed on the skin tumor sample was positive, and the complete PV genome was determined in the studied sample using next-generation sequencing technology. The analysis of the PV genome revealed infection of the stone marten with a putative new PV type belonging to the Dyonupapillomavirus genus. The proposed new stone marten PV type was named MfoiPV1.

Novel equid papillomavirus from domestic donkey

“…7 In several species, including humans and vertebrate animals, PVs can be associated with benign self-limited warts and neoplasms of the epithelial and mucous membranes. 8,9 While PV-induced lesions typically resolve spontaneously, they might occasionally lead to a more serious condition, such as malignancy. 10 PVs are believed to be one of the earliest viral families, co-evolving over millions of years with their hosts.…”