Identification of Antimicrobial Property of Rat-Tailed Maggots Surviving in Pig Excreta

Abstract

In the near future, antimicrobial resistance (AMR) will become a major danger to the global community. Despite the fact that India has many synthetic antibiotics, their irrational use is generating possible AMR in livestock. Furthermore, the expense of producing synthetic antibiotics is too expensive for the impoverished farming population. In this context, natural therapeutics are being sought. The current examination found that rat-tailed maggots from piggery excreta had antibacterial properties against Escherichia coli and Salmonella typhimurium, with minimum inhibitory concentrations (MIC) of 25–30 g/100 µl and 35–40 g/100 µl, respectively. Antimicrobial peptide sequences such as Diptericin and Sarcotoxin were also found in the isolated hemolymph. In comparison to rice grained shaped maggot hemolymphs, comparative gene expression levels for both AMPs were substantially (p < 0.05) increased in rat-tailed maggots. The current study's findings may suggest that using natural maggots in animal husbandry waste as a therapeutic alternative decreases the unjustified usage of antibiotics.