Identification of asymptomatic Leishmania infection in patients undergoing kidney transplant using multiple tests

Deni, Alessandro; De Pascali, Alessandra Mistral; Ortalli, Margherita; Balducelli, Emma; Provenzano, Michele; Ferrara, Francesca; Busutti, Marco; La Manna, Gaetano; Zammarchi, Lorenzo; Bartoloni, Alessandro; Caroti, Leonardo; Ibarra-Meneses, Ana Victoria; Carrillo, Eugenia; Comai, Giorgia; Varani, Stefania

doi:10.1016/j.ijid.2023.11.012

International Journal of Infectious Diseases

2024

DOI: 10.1016/j.ijid.2023.11.012

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Identification of asymptomatic Leishmania infection in patients undergoing kidney transplant using multiple tests

Alessandro Deni,

Alessandra Mistral De Pascali,

Margherita Ortalli

et al.

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2024

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Cited by 2 publications

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Accuracy evaluation of diagnostic methods for visceral leishmaniasis in adult patients with and without HIV infection: Clinical management implications

Druzian,

França,

Higa-Júnior

et al. 2024

Acta Tropica

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Accuracy evaluation of diagnostic methods for visceral leishmaniasis in adult patients with and without HIV infection: Clinical management implications

Druzian,

França,

Higa-Júnior

et al. 2024

Acta Tropica

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Leishmaniasis in transplant patients: what do we know so far?

Monge-Maillo,

López-Vélez

2024

Current Opinion in Infectious Diseases

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Purpose of review The number of cases of visceral leishmaniasis associated with transplant-associated immunosuppression has increased in recent years. Reviewing and updating the latest developments in its diagnostic management, treatment, and follow-up is necessary and relevant. Recent findings Visceral leishmaniasis cases associated with non-HIV immunosuppression are a growing cause of the parasitic infections, and the transplant patients are included in this context. These have been described especially in kidney transplantation. Liposomal amphotericin B is the first-line treatment. Due to immunosuppression, these patients often suffer from recurrent infections. The use of markers that indicate whether the patient has developed an adequate cellular response against Leishmania after treatment seems to be good biomarkers of cure and useful for monitoring and guiding secondary prophylaxis. Summary There is a lack of consensus regarding the need for leishmaniasis screening in donors and recipients and the indications for secondary prophylaxis. The study of new biomarkers of cure may be useful in all three contexts.

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Identification of asymptomatic Leishmania infection in patients undergoing kidney transplant using multiple tests

Cited by 2 publications

References 10 publications

Accuracy evaluation of diagnostic methods for visceral leishmaniasis in adult patients with and without HIV infection: Clinical management implications

Accuracy evaluation of diagnostic methods for visceral leishmaniasis in adult patients with and without HIV infection: Clinical management implications

Leishmaniasis in transplant patients: what do we know so far?

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