2020
DOI: 10.21203/rs.3.rs-16069/v6
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Identification of ATP2C1 mutations in the patients of Hailey-Hailey disease

Abstract: Background: Familial benign chronic pemphigus, also known as Hailey-Hailey disease (HHD), is a clinically rare bullous Dermatosis. However the mechanism has not been clarified. The study aim to detect novel mutations in exons of ATP2C1 gene in HHD patients; to explore the possible mechnism of HHD pathogenesis by examining the expression profile of hSPCA1, miR-203, p63, Notch1 and HKⅡ proteins in the skin lesions of HHD patients. Methods: Genomic DNA was extracted from peripheral blood of HHD patients. All exon… Show more

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(2 citation statements)
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“…In light of emergence [50], larger models are however often preferable. We are already able to extract 73% and 47% of the text and code samples, even larger models like CodeX [14] or Starcoder [34] might memorise even more data.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In light of emergence [50], larger models are however often preferable. We are already able to extract 73% and 47% of the text and code samples, even larger models like CodeX [14] or Starcoder [34] might memorise even more data.…”
Section: Discussionmentioning
confidence: 99%
“…This risk extends to pre-trained models, as some pre-training corpora, including the Pile [22], also contain code licenced under non-permissive licences [2]. The risk can be avoided by training models with code licenced under permissive licences (such as BSD-3 or MIT) or providing provenance information to trace the code back to its source so that the user of the output can abide by the original licence [23,34].…”
Section: Discussionmentioning
confidence: 99%