Identification of bacterial microflora in the midgut of the larvae and adult of wild caught Anopheles stephensi: A step toward finding suitable paratransgenesis candidates

Chavshin, Ali Reza; Oshaghi, Mohammad Ali; Vatandoost, Hassan; Pourmand, Mohammad Reza; Ahmad, Rasheed; Enayati, Ahmadali; Mardani, N; Ghoorchian, S

doi:10.1016/j.actatropica.2011.10.015

Cited by 117 publications

(99 citation statements)

References 28 publications

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“…The normal midgut microbiota of Anopheles mosquitoes need to be further identified [5] as only few studies have reported the microbiota of wild caught malaria vectors (Table 1) [5-7, 9, 11, 12, 17, 24, 26-29, 31-35]. Further investigations of gut microbiota, especially of wild-caught insect vectors, might contribute to understanding the annual and regional variations recorded for vector transmitted diseases [17] and yield novel vector-control strategies [14].…”

Section: Midgut Microbiome Of Mosquitoesmentioning

confidence: 99%

“…Recent studies showed that one of these factors concerns the primordial role played by the bacteria naturally present in mosquito midgut. Then, there is a growing interest on bacterial biodiversity in Anopheles mosquitoes and particularly those based on the identification of bacteria to be used for malaria transmission blocking based on bacterial genetic changes to deliver antiparasite molecules or paratransgenic approach [5][6][7][8][9][10][11][12][13]. Recent studies reported the presence of symbiotic bacteria, such as Pantoea agglomerans or Asaia in midgut lumen with anti-Plasmodium effector proteins that render host mosquitoes refractory to malaria infection [6,10,13].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bacterial Biodiversity in Midguts of Anopheles Mosquitoes, Malaria Vectors in Southeast Asia

Manguin¹,

Ngo²,

Tainchum³

et al. 2013

Anopheles Mosquitoes - New Insights Into Malaria Vectors

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Section: Midgut Microbiome Of Mosquitoesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bacterial Biodiversity in Midguts of Anopheles Mosquitoes, Malaria Vectors in Southeast Asia

Manguin¹,

Ngo²,

Tainchum³

et al. 2013

Anopheles Mosquitoes - New Insights Into Malaria Vectors

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“…Some are newly identified bacterial species, and extensive studies are rapidly increasing the number of potential candidates to be used in paratransgenic approaches to control MBD. [21][22][23][24] To develop such approaches, it is also possible to refer to other microorganisms rather than bacterial endosymbionts; viruses, fungi, and yeasts have recently been proposed. Densoviruses, capable of infecting and disseminating in Anopheles gambiae, have been recently proposed as a paratransgenic tool for malaria control strategies.…”

Section: Manipulation Of Symbionts To Express Antipathogen Molecules mentioning

confidence: 99%

Symbiotic control of mosquito borne disease

Ricci

Valzano

Ulissi

et al. 2012

Pathogens and Global Health

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It is well accepted that the symbiotic relationships insects have established with several microorganisms have had a key role in their evolutionary success. Bacterial symbiosis is also prevalent in insects that are efficient disease vectors, and numerous studies have sought to decrypt the basic mechanisms of the hostsymbiont relationships and develop ways to control vector borne diseases. 'Symbiotic control', a new multifaceted approach that uses symbiotic microorganisms to control insect pests or reduce vector competence, seems particularly promising. Three such approaches currently at the cutting edge are: (1) the disruption of microbial symbionts required by insect pests; (2) the manipulation of symbionts that can express anti-pathogen molecules within the host; and (3) the introduction of endogenous microbes that affect life-span and vector capacity of the new hosts in insect populations. This work reviews current knowledge on microbial symbiosis in mosquitoes that holds promise for development of symbiotic control for mosquito borne diseases.

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“…In the last decade, multiple relevant studies have been published, ranging from diversity screening using metagenomic surveys (Baumann 2005, Lindh et al 2005, Carpi et al 2011, Djadid et al 2011, Lindh & Lehane 2011, Ng et al 2011a, b, Chavshin et al 2012) to molecular studies of the interaction of gut bacteria with the host immune system and the response to infection (Azambuja et al 2005, Chouaia et al 2010, Cirimotich et al 2011, Boissière et al 2012). In addition to the native gut microbiota, symbiotic bacteria occupy other key organs, tissues or structures (e.g., salivary glands, ovaries, haemolymph).…”

mentioning

confidence: 99%

Metagenomics, paratransgenesis and the Anopheles microbiome: a portrait of the geographical distribution of the anopheline microbiota based on a meta-analysis of reported taxa

Villegas

Pimenta

2014

Mem. Inst. Oswaldo Cruz

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Anophelines harbour a diverse microbial consortium that may represent an extended gene pool for the host. The proposed effects of the insect microbiota span physiological, metabolic and immune processes. Here we synthesise how current metagenomic tools combined with classical culture-dependent techniques provide new insights in the elucidation of the role of the Anopheles-associated microbiota. Many proposed malaria control strategies have been based upon the immunomodulating effects that the bacterial components of the microbiota appear to exert and their ability to express anti-Plasmodium peptides. The number of identified bacterial taxa has increased in the current “omics” era and the available data are mostly scattered or in “tables” that are difficult to exploit. Published microbiota reports for multiple anopheline species were compiled in an Excel® spreadsheet. We then filtered the microbiota data using a continent-oriented criterion and generated a visual correlation showing the exclusive and shared bacterial genera among four continents. The data suggested the existence of a core group of bacteria associated in a stable manner with their anopheline hosts. However, the lack of data from Neotropical vectors may reduce the possibility of defining the core microbiota and understanding the mosquito-bacteria interactive consortium.

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Identification of bacterial microflora in the midgut of the larvae and adult of wild caught Anopheles stephensi: A step toward finding suitable paratransgenesis candidates

Cited by 117 publications

References 28 publications

Bacterial Biodiversity in Midguts of Anopheles Mosquitoes, Malaria Vectors in Southeast Asia

Bacterial Biodiversity in Midguts of Anopheles Mosquitoes, Malaria Vectors in Southeast Asia

Symbiotic control of mosquito borne disease

Metagenomics, paratransgenesis and the Anopheles microbiome: a portrait of the geographical distribution of the anopheline microbiota based on a meta-analysis of reported taxa

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