Identification of bioactive compounds in leaf extract of Avicennia alba by GC-MS analysis and evaluation of its in-vitro anticancer potential against MCF7 and HeLa cell lines

Anti-cancer activity of biosynthesized silver nanoparticles using Avicennia marina against A549 lung cancer cells through ROS/mitochondrial damages

“…The result was proved that the Ag NPs was concentration dependent inhibitor agent for A549 cells. In addition, 54% of inhibition was observed at 50 µg/mL and it was comparatively low than previous reports ( Eswaraiah et al, 2020 , Momtazi-borojeni et al, 2103 ). Previously, Momtazi-borojeni reported that the crude extract of Avicennia marina exhibited with excellent anti-cancer properties at 250 µg/mL.…”

“…To try to overcome this problem, marine mangrove plant Avicennia marina mediated Ag NPs has indicated as a promising alternative solution to fight against cancer cells, without any side effects ( Behbahani et al, 2018 ). Previous reports also supported to the plant A. marina has excellent potential biomedical agent with anti-microbial, anti-tumor, cytotoxic, anthelmintic, analgesic, anti-inflammatory, hypertensive, immune stimulatory and anti-cancer activities ( Manilal et al, 2016 , Eswaraiah et al, 2020 ). Interestingly, there is no previous report on the biosynthesis of Ag NPs from marine mangrove plant A. marina against A549 human lung cancer cell lines ( Momtazi-borojeni et al, 2103 ).…”

“…It inhibited the cancer cells at very lowest concentration due to the unexplored nature of mangrove plant containing biochemical components, nutrients, pH, temperature and other stress responses factor ( Naveen kumar et al, 2018a , Naveen kumar et al, 2018b ). Recently, Eswaraiah et al, 2020 reported that the marine mangrove plant Avicennia marina has anti-cancer properties against various cancer cells. It enhanced the anti-cancer activity than other plant and chemical synthesized Ag NPs due to the fluctuated marine environmental conditions such as temperature, salinity, pH, carbon and nitrogen sources ( Ramachandran et al, 2018 ).…”

“…Marine mangrove plant Avicennia marina is an important plant which grows in difficult environment condition such as high salt, pH, temperature, and excess carbon and nitrogen sources. It is used in pharmaceutical application and led the detection of variety of phytochemicals as effective chemo-preventive agents for different biological activities, particularly effective against cancer cells ( Eswaraiah et al, 2020 ). It is an excellent reducing agents used as a reducing agents for various nanoparticle synthesis.…”

Screening of Ipomoea tuba Leaf Extract for Identification of Bioactive Compounds and Evaluation of Its in vitro Antiproliferative Activity Against MCF-7 and HeLa Cells

“…Mangrove ecosystem plays a major role in the human life to protect us from natural disasters like tsunami, floods, high tides and soil erosion. Mangrove plants grow in water logging region and offer a shelter for wide ranges of endemic fauna and flora ( 1 , 2 ). They absorb and remove five times more carbon dioxide than normal terrestrial plants ( 3 ).…”