Identification of Bioactive Peptides in Mussel Species of Kanyakumari Coast

Jeyasanta, Immaculate; Sathish, Narmatha; Patterson, Jamila

doi:10.3923/ajbkr.2020.75.86

Cited by 3 publications

(2 citation statements)

References 32 publications

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“…The hydrolysate obtained from abalone viscera yielded peptides with high molecular weight (~ 200–116.25 kDa), medium molecular weight (~ 116.25–66.25 kDa), and low molecular weight (~ 66.2–31.0 kDa) molecular weight peptides. Medium and low molecular weight peptides have been related with antimicrobial activity in various marine species, including the oyster Crassostrea gigas 47 , marine snail Cenchritis muricatus 48 , and mussel species Perna viridis and P. perna 49 . Aqueous extracts from marine mollusks have shown inhibitory activity against Gram-positive and Gram-negative strains, such as Klebsiella pneumoniae and Salmonella typhi ( Melo melo 50 , Vibrio parahaemolyticus and, Staphylococcus aureus and Candida albicans ( Babilonia spyrata 51 ), E. coli, S. aureus , B. subtilis, S. pneumonia, and P. aeruginosa , ( G. paradoxa 52 ).…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial and anticarcinogenic activity of bioactive peptides derived from abalone viscera (Haliotis fulgens and Haliotis corrugata)

Rivera-Pérez,

Ponce González,

Hernández-Savedra

2023

Sci Rep

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Bioactive peptides have been studied in several sources due to their valuable potential in the pharmaceutical and food industries. Abalone viscera, which are normally discarded as byproducts, are a rich source of protein. Thus, the aim of this study was to explore the potential bioactivity of peptides derived from abalone viscera (Haliotis fulgens and Haliotis corrugata) after hydrolysis with a commercial mixture of enzymes. The hydrolysates obtained were fractionated using gel filtration chromatography. The resulting hydrolysate fractions were investigated for their antimicrobial and cytotoxic activities, including the expression of gelatinases mmp-2 and mmp-9 in human prostate cancer cell lines (PC3). Results showed antimicrobial activity for protein fractions of H. corrugata against Proteus mirabilis and Pseudomona aeuroginosa (66.2–116.25 kDa), Bacillus subtilis (6.5–21.5 kDa), and Aspergillus niger (97.4–116.25 kDa), while H. fulgens peptide fractions (200–31 kDa) displayed activity against six bacterial strains, and fractions from 116.25 to 21.5 kDa had effects on the fungus A. niger, Alternaria alternata, and Aspergillus flavus. Additionally, protein fractions displayed cytotoxic activity, inhibiting 30.4–53.8% of PC3 cellular growth. Selected fractions decreased the PMA-induced and not-induced expressions of mmp-2 and mmp-9 in PC3 cells. Abalone viscera, as byproducts, can be used as a potential source of antimicrobial and anticancer peptides.

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Section: Discussionmentioning

confidence: 99%

Antimicrobial and anticarcinogenic activity of bioactive peptides derived from abalone viscera (Haliotis fulgens and Haliotis corrugata)

Rivera-Pérez,

Ponce González,

Hernández-Savedra

2023

Sci Rep

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“…It is notable that the sequential treatment of seaweeds with acid and alkaline solutions improves protein extraction efficiency [17]. However, in some cases, treatment with acid solutions only showed higher protein retrieval when using various solvents such as methanol, acetone, ethanol, hexane-ethyl acetate, and butanol [25]. Among other solvents, methanol was found to be effective in peptide separation with anti-microbial properties against 13 distinct pathogenic bacteria.…”

Section: Solvent Extractionmentioning

confidence: 99%

Development of Bioactive Peptides Derived from Red Algae for Dermal Care Applications: Recent Advances

et al. 2023

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Bioactive peptides produced from proteinaceous red algae biomass with varied structures have garnered much attention in biological applications and production. Unfortunately, there have been few studies on developing approaches to feasible bioactive peptide production and purification. Our goal with this article is to explore the latest trends in easily applicable approaches for extracting bioactive peptides for cutaneous applications. Bibliometric statistics show that the number of scientific publications is growing, with Asia ranking as the highest producer. Peptide purity and bioactivity are the most important factors to consider while extracting and identifying peptides using various separation techniques. To generate novel bioactive peptides with high yield and low cost, future research should focus on increasing the yields and improving the separation methods. Moreover, human clinical trials should be conducted to validate their potential health benefits. Thus, the final objective of this literature review was to give an insight into the bioactive properties of red algae-derived peptides, which have proven potential for dermal application with anti-melanogenic, collagenogenic, antioxidant, antiaging, and photoprotective activities, etc. Moreover, it covers the algal peptides’ scope for use in nutraceuticals and pharmaceuticals, and future studies for their emerging applications.

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Recent developments on production, purification and biological activity of marine peptides

Sridhar

Inbaraj

Chen

2021

Food Research International

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Identification of Bioactive Peptides in Mussel Species of Kanyakumari Coast

Cited by 3 publications

References 32 publications

Antimicrobial and anticarcinogenic activity of bioactive peptides derived from abalone viscera (Haliotis fulgens and Haliotis corrugata)

Antimicrobial and anticarcinogenic activity of bioactive peptides derived from abalone viscera (Haliotis fulgens and Haliotis corrugata)

Development of Bioactive Peptides Derived from Red Algae for Dermal Care Applications: Recent Advances

Recent developments on production, purification and biological activity of marine peptides

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