2016
DOI: 10.1016/j.ijid.2016.02.143
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Identification of biofilm-stage specific proteins associated with multidrug resistance and quorum sensing pathway in a pandemic strain of Vibrio parahaemolyticus isolated from India

Abstract: EC (25%), FQ (20%), CAR (4%), and DAP (133%) occured. In 2010, AMT was re-implemented and resulted in 12 and 15% reduction in total AE. Cost savings exceeded $300,000.From 2010 to 2014, we have implemented multiple strategies to further control AU. Conclusion:Since 2004, AMT has implemented strategies that reduced the consumption of RAP agents and Pseudmonas resistance has not increased. Re-implementation of AMT responsible for administering institutional guidelines and providing direct feedback resulted in ra… Show more

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“…S1, Table 1). This suggests that resistance of V. parahaemolyticus to antimicrobial agents is a consequence of elevated biofilm production (Dharmaprakash and Thomas, 2016), which could possibly be mediated by shear stress-induced levan production (Guo and Gross, 2014;Kemper et al, 2014), although other mechanisms like enzyme-related resistance, genetic adaptation or limited diffusion of antimicrobial agents through the biofilm matrix are potentially possible (Vilain et al, 2002;Hall and Mah, 2017;Singh et al, 2017).…”
Section: Discussionmentioning
confidence: 99%
“…S1, Table 1). This suggests that resistance of V. parahaemolyticus to antimicrobial agents is a consequence of elevated biofilm production (Dharmaprakash and Thomas, 2016), which could possibly be mediated by shear stress-induced levan production (Guo and Gross, 2014;Kemper et al, 2014), although other mechanisms like enzyme-related resistance, genetic adaptation or limited diffusion of antimicrobial agents through the biofilm matrix are potentially possible (Vilain et al, 2002;Hall and Mah, 2017;Singh et al, 2017).…”
Section: Discussionmentioning
confidence: 99%