Identification of cannabinoids in post-mortem blood samples from the province of New Brunswick before and after recreational cannabis legalization

Jordan, Alexander; Sherazi, Ali; Flewelling, Andrew J.; Northrup, Victoria; Naseemuddin, Ather; Shea, Jennifer

doi:10.1016/j.drugpo.2022.103629

Cited by 4 publications

(6 citation statements)

References 35 publications

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“…59 Finally, a Canadian study that examined cannabinoids in post-mortem blood samples reported that post-RCL deaths had higher odds of positive cannabis post-mortem screens compared to pre-RCL (95% CI: 1.09-1.73). 93 However, the majority of growth for positive cannabinoid screens took place in the two years prior to RCL implementation. In sub-group analyses, only 25- to 44-year-olds had a significant increase in positive cannabinoid screens (95% CI: 0.05-0.19).…”

Section: Resultsmentioning

confidence: 99%

The Impact of Recreational Cannabis Legalization on Cannabis Use and Associated Outcomes: A Systematic Review

et al. 2023

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Background: Recreational cannabis legalization has become more prevalent over the past decade, increasing the need to understand its impact on downstream health-related outcomes. Although prior reviews have broadly summarized research on cannabis liberalization policies (including decriminalization and medical legalization), directed efforts are needed to synthesize the more recent research that focuses on recreational cannabis legalization specifically. Thus, the current review summarizes existing studies using longitudinal designs to evaluate impacts of recreational cannabis legalization on cannabis use and related outcomes. Method: A comprehensive bibliographic search strategy revealed 61 studies published from 2016 to 2022 that met criteria for inclusion. The studies were predominantly from the United States (66.2%) and primarily utilized self-report data (for cannabis use and attitudes) or administrative data (for health-related, driving, and crime outcomes). Results: Five main categories of outcomes were identified through the review: cannabis and other substance use, attitudes toward cannabis, health-care utilization, driving-related outcomes, and crime-related outcomes. The extant literature revealed mixed findings, including some evidence of negative consequences of legalization (such as increased young adult use, cannabis-related healthcare visits, and impaired driving) and some evidence for minimal impacts (such as little change in adolescent cannabis use rates, substance use rates, and mixed evidence for changes in cannabis-related attitudes). Conclusions: Overall, the existing literature reveals a number of negative consequences of legalization, although the findings are mixed and generally do not suggest large magnitude short-term impacts. The review highlights the need for more systematic investigation, particularly across a greater diversity of geographic regions.

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Section: Resultsmentioning

confidence: 99%

The Impact of Recreational Cannabis Legalization on Cannabis Use and Associated Outcomes: A Systematic Review

et al. 2023

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“…In most cases, the authors were unable to adjust for other potential factors that may have explained the changes observed post‐legalization. For example, increased cannabis‐related presentations may have been associated with increased testing and reporting [ 12 , 13 ]. The same may have been true of studies of THC detected when driving because of increased testing rates post‐legalization and because THC measured in blood or urine may not necessarily cause impairment.…”

Section: Resultsmentioning

confidence: 99%

“…We summarized findings from five studies of presentations to hospital EDs for cannabis-induced psychosis and mental health presentations, a study of cannabis-positive cases postmortem in Coroner's cases and cannabis-related hospitalizations [13,[39][40][41][42]. Vignault et al [42] assessed the short-term impact of the legalization on cannabis use, cannabis use disorder and psychotic disorders among patients in one Quebec hospital before and 5 months after cannabis use was legalized.…”

Section: Health Service Presentationsmentioning

confidence: 99%

“…We summarized findings from five studies of presentations to hospital EDs for cannabis‐induced psychosis and mental health presentations, a study of cannabis‐positive cases postmortem in Coroner's cases and cannabis‐related hospitalizations [ 13 , 39 , 40 , 41 , 42 ]. Vignault et al .…”

Section: Public Health and Safety After Legalizationmentioning

confidence: 99%

“…Jordan et al[13] examined changes in the postmortem detection of cannabinoids in 3060 deaths in the province of New Brunswick…”

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confidence: 99%

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The implementation and public health impacts of cannabis legalization in Canada: a systematic review

et al. 2023

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AimsWe provide a narrative summary of research on changes in cannabis arrests, cannabis products and prices, cannabis use and cannabis‐related harm since legalization.MethodsWe systematically searched for research on the impacts of cannabis legalization in Canada in PubMed, Embase, Statistics Canada and government websites and Google Scholar, published between 2006 and 2021.ResultsCannabis legalization in Canada has been followed by substantial reductions in cannabis‐related arrests and cannabis prices. It has also increased adults’ access to a diverse range of cannabis products, including edibles and extracts. The prevalence of cannabis use among young adults has increased, but there have been no marked increases or decreases in use among high school students or changes in the prevalence of daily or near‐daily use. Legalization has been associated with increased adult hospital attendances for psychiatric distress and vomiting, unintentional ingestion of edible cannabis products by children and hospitalizations for cannabis use disorders in adults. There is conflicting evidence on whether cannabis‐impaired driving has increased since legalization. There is suggestive evidence that presentations to emergency departments with psychoses and cannabis use disorders may have increased since legalization.ConclusionsLegalization of cannabis in Canada appears to have reduced cannabis arrests and increased access to a variety of more potent cannabis products at lower prices. Since 2019, recent cannabis use in Canada has modestly increased among adults but not among adolescents. There is evidence of increased acute adverse effects of cannabis among adults and children.

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Cannabis-involvement in emergency department visits for self-harm following medical and non-medical cannabis legalization

Myran,

Gaudreault,

Pugliese

et al. 2024

Journal of Affective Disorders

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Identification of cannabinoids in post-mortem blood samples from the province of New Brunswick before and after recreational cannabis legalization

Cited by 4 publications

References 35 publications

The Impact of Recreational Cannabis Legalization on Cannabis Use and Associated Outcomes: A Systematic Review

The Impact of Recreational Cannabis Legalization on Cannabis Use and Associated Outcomes: A Systematic Review

The implementation and public health impacts of cannabis legalization in Canada: a systematic review

Cannabis-involvement in emergency department visits for self-harm following medical and non-medical cannabis legalization

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