Identification of carbohydrate and nucleic acid biomarkers in the pyrolysis electron ionization-high-resolution mass spectrum of Brucella neotomae

Abbas‐Hawks, Christy; Voorhees, Kent J.; Miketová, Petra

doi:10.1016/j.jaap.2005.06.008

Cited by 5 publications

(1 citation statement)

References 31 publications

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“…Pyrolysis products that derive from carbohydrates (Abbas-Hawks, Voorhees, & Miketova, 2006), lipids (Voorhees et al, 2006b), nucleic acids (Abbas-Hawks, Voorhees, & Miketova, 2006), proteins (Voorhees, Abbas-Hawks, & Miketova, 2006a), and other components, such as dipicolinic or poly(3-hydroxyalkanoic) acids, have been utilized to differentiate bacteria. Goodacre et al (2000) detected the dipicolinic acid biomarker in 36 Bacillus species with Py-MS. An ion-mobility spectrometer (IMS) has been employed as a detector in the Py-GC analysis of bacteria in the on-site monitoring of transient plumes of aerosols that contain B. subtilis (Snyder et al, 2004).…”

Section: Pyrolysis-gc-msmentioning

confidence: 99%

Advances in mass spectrometry for the identification of pathogens

Reddy

2011

Mass Spectrometry Reviews

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Mass spectrometry (MS) has become an important technique to identify microbial biomarkers. The rapid and accurate MS identification of microorganisms without any extensive pretreatment of samples is now possible. This review summarizes MS methods that are currently utilized in microbial analyses. Affinity methods are effective to clean, enrich, and investigate microorganisms from complex matrices. Functionalized magnetic nanoparticles might concentrate traces of target microorganisms from sample solutions. Therefore, nanoparticle-based techniques have a favorable detection limit. MS coupled with various chromatographic techniques, such as liquid chromatography and capillary electrophoresis, reduces the complexity of microbial biomarkers and yields reliable results. The direct analysis of whole pathogenic microbial cells with matrix-assisted laser desorption/ionization MS without sample separation reveals specific biomarkers for taxonomy, and has the advantages of simplicity, rapidity, and high-throughput measurements. The MS detection of polymerase chain reaction (PCR)-amplified microbial nucleic acids provides an alternative to biomarker analysis. This review will conclude with some current applications of MS in the identification of pathogens.

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Section: Pyrolysis-gc-msmentioning

confidence: 99%

Advances in mass spectrometry for the identification of pathogens

Reddy

2011

Mass Spectrometry Reviews

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Current literature in mass spectrometry

2007

J. Mass Spectrom.

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INSTRUMENTAL TECHNIQUES & METHODSAl-Lawati H, Watts P, Welham KJ. Efficient protein digestion with peptide separation in a micro-device interfaced to electrospray mass spectrometry. [127][128][129][130][131][132][133][134][135][136][137][138] Published online in Wiley InterScience (www.interscience.wiley.com). DOI:10.1002DOI:10. /jms.1070 Current literature in mass spectrometry (6 weeks journals -Search completed at 4th. Oct. 2006) In order to keep subscribers up-to-date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of mass spectrometry. Each bibliography is divided into 11 sections: 1 Books, Reviews & Symposia; 2 Instrumental Techniques & Methods; 3 Gas Phase Ion Chemistry; 4 Biology/Biochemistry: Amino Acids, Peptides & Proteins; Carbohydrates; Lipids; Nucleic Acids; 5 Pharmacology/Toxicology; 6 Natural Products; 7 Analysis of Organic Compounds; 8 Analysis of Inorganics/Organometallics; 9 Surface Analysis; 10 Environmental Analysis; 11 Elemental Analysis. Within each section, articles are listed in alphabetical order with respect to author. Larsen BS, Stchur P, Szostek B, Bachmura SF, Rowand RC, Prickett KB, Korzeniowski SH, Buck RC. Method development for the determination of residual fluorotelomer raw materials and perfluorooctanoate in fluorotelomerbased products by gas chromatography and liquid chromatography mass spectrometry. ANALYSIS OF ORGANIC COMPOUNDS

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Analytical pyrolysis of nucleic acids

Moldoveanu¹

2021

Analytical Pyrolysis of Natural Organic Polymers

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Identification of carbohydrate and nucleic acid biomarkers in the pyrolysis electron ionization-high-resolution mass spectrum of Brucella neotomae

Cited by 5 publications

References 31 publications

Advances in mass spectrometry for the identification of pathogens

Advances in mass spectrometry for the identification of pathogens

Current literature in mass spectrometry

Analytical pyrolysis of nucleic acids

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