The perspective of using the photoplethysmographic method for evaluating microcirculatory changes in tissue microcirculation to study the processes that occur during photon physiotherapeutic influence in the maxillofacial region is considered. Also, this research method is relevant for determining microcirculation disorders in patients with various degrees of severity of field injuries. 2. Photon radiation has been shown to increase the elasticity of blood vessel walls, elasticity of erythrocytes, oxygen transport function of blood, activity of cell membranes, acceleration of tissue regeneration processes, reduction of lipid oxidation, normalization of blood rheological parameters, stimulation of ATP formation in mitochondria, which increases the bioenergetic potential of cells.