2024
DOI: 10.1186/s12864-024-10122-7
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Identification of common stria vascularis cellular alteration in sensorineural hearing loss based on ScRNA-seq

Xi Gu,
Kanglun Jiang,
Ruru Chen
et al.

Abstract: Background The stria vascularis (SV), located in the lateral wall of the cochlea, maintains cochlear fluid homeostasis and mechanoelectrical transduction (MET) activity required for sound wave conduction. The pathogenesis of a number of human inheritable deafness syndromes, age related hearing loss, drug-induced ototoxicity and noise-induced hearing loss results from the morphological changes and functional impairments in the development of the SV. In this study, we investigate the implications… Show more

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