Identification of Esophagitis Dissecans Superficialis by Endoscopy

Brownschidle, Sara; Ganguly, Eric K.; Wilcox, Rebecca

doi:10.1016/j.cgh.2014.02.030

Cited by 14 publications

(17 citation statements)

References 6 publications

(10 reference statements)

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“…However, the direct mechanism of esophageal injury in EDS remains unclear. Pathogenesis of EDS might be a result of direct insult to the esophageal mucosa through physical, chemical, thermal, immunological mechanisms, or associated with a topical or ischemic injury [4, 5]. EGD classically shows a stripped off mucosal appearance in the esophagus.…”

Section: Discussionmentioning

confidence: 99%

Fungal Esophagitis Presenting With Esophagitis Dissecans Superficialis: Cause or Concurrence? A Diagnostic Conundrum

et al. 2016

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Esophagitis dissecans superficialis (EDS) is a rare desquamative disorder of the esophagus. It is characterized by sheets of sloughed squamous tissue with normal underlying mucosa. We present a case of a 68-year-old man with severe anemia and a positive fecal occult blood test who was found to have features suggestive of EDS during endoscopy. However, histological features were suggestive of both EDS and fungal esophagitis. To our knowledge, this is the first reported case in literature which discusses the clinical scenario of fungal infection being a possible etiology rather than a commonly accepted differential diagnosis of EDS. We also review the clinical features, diagnostic criteria and treatment of EDS.

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Section: Discussionmentioning

confidence: 99%

Fungal Esophagitis Presenting With Esophagitis Dissecans Superficialis: Cause or Concurrence? A Diagnostic Conundrum

et al. 2016

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“…There has been a single reported case of EDS related to severe methotrexate toxicity with folate deficiency and pancytopenia, which improved after rescue folinic acid and discontinuation of methotrexate [6,7]. Our patient was on low-dose weekly methotrexate (7.5 mg) along with folic acid supplementation started around nine months prior to the presentation.…”

Section: Discussionmentioning

confidence: 84%

“…There is no recommendation for a specific therapy or follow-up. Mucosal healing can be achieved through a combination of acid suppression and discontinuation of the precipitating factors and medications [6,7].…”

Section: Discussionmentioning

confidence: 99%

Esophagitis Dissecans Superficialis: Malign Appearance of a Benign Pathology

Rokkam

Aggarwal

Taleban

2020

Cureus

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Esophagitis dissecans superficialis (EDS), also known as sloughing esophagitis, is a very rare condition and may affect the whole esophagus, resulting in complete sloughing of the mucous membrane. EDS has been associated with various medications and dermatological conditions. In our case, EDS was suspected secondary to methotrexate treatment in a patient with Crohn's disease, although the definitive etiology remains unknown. It is very important for physicians to recognize the endoscopic appearance of EDS to provide appropriate clinical management and differentiate it from other esophageal disorders.

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“…In addition, we review all 30 adult patients (including our case) with EDS [1, 4, 5, 7–11] (Table 1). There were 15 males and 15 females with the mean age of 65.8 ± 14.9 (range: 42–88) years.…”

Section: Discussionmentioning

confidence: 99%

First Case of Esophagitis Dissecans Superficialis in an HIV Patient: A Case Report and Literature Review

Prasoppokakorn

Panarat²

2019

Case Reports in Infectious Diseases

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Esophagitis dissecans superficialis (EDS), a rare desquamative esophageal disease of uncertain etiology, is characterized by sloughing of fragments of esophageal mucosa. To the best of our knowledge, there has been no reported case of EDS in an HIV-infected patient. We report the first case of EDS in an adult HIV-infected male, who was hospitalized due to dysphagia. Esophagogastroscopy was performed, and the endoscopic findings together with the histopathologic findings of esophageal tissues were consistent with EDS. However, his symptom of dysphagia was not explained by EDS, but was the early symptoms of muscle-specific kinase (MuSK) myasthenia gravis (MG) that we finally diagnosed later by progression of the symptoms and electrophysiologic study. His symptoms had gradually improved after a course of intravenous immunoglobulin treatment. This is the first case of EDS and MuSK myasthenia gravis in an HIV-infected patient. A high index of suspicion of EDS should be made when taking care of the patients with desquamative or sloughing esophagitis especially with unknown etiology.

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Identification of Esophagitis Dissecans Superficialis by Endoscopy

Cited by 14 publications

References 6 publications

Fungal Esophagitis Presenting With Esophagitis Dissecans Superficialis: Cause or Concurrence? A Diagnostic Conundrum

Fungal Esophagitis Presenting With Esophagitis Dissecans Superficialis: Cause or Concurrence? A Diagnostic Conundrum

Esophagitis Dissecans Superficialis: Malign Appearance of a Benign Pathology

First Case of Esophagitis Dissecans Superficialis in an HIV Patient: A Case Report and Literature Review

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