Identification of F13A1 and SCCPDH as Potential Diagnostic Markers for Preeclampsia
Yihan Zheng,
Zhuanji Fang,
Xizhu Wu
et al.
Abstract:Preeclampsia (PE) is a serious condition that affects pregnant women worldwide. This study aimed to identify diagnostic candidate genes for PE. Gene expression from a PE cohort and controls was analyzed using Limma and weighted gene coexpression network analysis (WGCNA) to identify differentially expressed genes (DEGs) and module genes. Machine learning techniques were then used to identify immune-associated hub genes for PE diagnosis, resulting in the selection of two significant genes (F13A1 and SCCPDH). A n… Show more
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