“…Based on the relative lower abundance of fragment ion [M + H–R 2 COOH] + caused by the neutral loss of FA at the sn-2 position, it was possible to distinguish the regioisomers of TG molecules. 36,37 Cer and HexCer, as the essential structural components of the lipid bilayer of the cell membrane, play an important role in many cellular processes throughout the life cycle. 38 Sphingolipids contain a fatty acyl chain (FA), which is linked to a long chain base (LCB) through an amide bond.…”