Identification of functional group present in <i>Andrographis paniculata</i> (kalmegh) leaves by FTIR analysis

Maria, M.F.F.; Ikhmal, W M K W M; Sabri, M. G. M.; Ibrahim, Muhamad Syazlie Che; Adnan, Azila

doi:10.1088/1757-899x/440/1/012035

Cited by 11 publications

(6 citation statements)

References 7 publications

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“…The peak at 2168 can be correlated to alkynes. The peak 3351 can be correlated to O-H group shows a group present in the andrographolide which is a highly reactive group and is responsible for H 2 O adsorption [24]. As a result, it is possible to deduce that andrographolides are responsible for capping and efficient stabilization.…”

Section: Ft-ir (Fourier Transform Infrared Spectrophotometry)mentioning

confidence: 98%

Methylene Blue Dye Degradation Using Silver Nanoparticles Synthesized from Andographis Paniculata Leaves Extract

Noorafsha¹,

Shukla²,

Kashyap³

et al. 2021

JPRI

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Today, the ejection of hazardous dyes from textile industries in water reservoirs like rivers, lakes and groundwater has become a severe problem. To remove these pollutants is challenging by classical water treatment procedures. Thus, for effluent treatment, we need a more convenient method. Here, we describe use of green synthesized silver nanoparticles in the degradation of precarious dye like methylene blue. The silver nanoparticles synthesized from leaves extract of andographis paniculata which act as a nanocatalyst. The synthesis of silver nanoparticles (AgNPs) and the reduction of silver ions are studied using UV-Visible spectroscopy (Ultraviolet-Visible spectroscopy) and FT-IR spectroscopy (Fourier Transform Infrared spectroscopy) respectively. Organic compounds are responsible for the capping and reduction of silver nanoparticles, according to Fourier Transform infrared spectra. The report accentuate that the AgNPs examined to be an effective catalyst for reduction of precarious dyes nearly 84% at 16 hrs of exposure time.

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Section: Ft-ir (Fourier Transform Infrared Spectrophotometry)mentioning

confidence: 98%

Methylene Blue Dye Degradation Using Silver Nanoparticles Synthesized from Andographis Paniculata Leaves Extract

Noorafsha¹,

Shukla²,

Kashyap³

et al. 2021

JPRI

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“…Besides that, the metal composition and content in A. paniculata is also responsible for its medicinal properties and its toxicity (Mythili et al 2011). Several previous studies have reported the metal content (Mythili et al 2011) and metabolite profile of A. paniculata (Chua et al 2013;Song et al 2013;Yusof et al 2015;Aneesh et al 2018;Maria et al 2018;Tajidin et al 2019;Rafi et al 2020a;Rafi et al 2020b). Those studies only reported the metabolite profile of A. paniculata and the differences in the composition and concentration of metabolites because of different plant parts and age, harvest time, mature and young leaves, and solvent extraction.…”

Section: Introductionmentioning

confidence: 99%

Inhibition of α-glucosidase activity, metals content, and phytochemical profiling of Andrographis paniculata from different geographical origins based on FTIR and UHPLC-Q-Orbitrap HRMS metabolomics

et al. 2021

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Abstract. Rafi M, Septaningsih DA, Karomah AH, Lukman, Prajogo B, Amran MB, Rohman A. 2021. Inhibition of α-glucosidase activity, metals content, and phytochemical profiling of Andrographis paniculata from different geographical origins based on FTIR and UHPLC-Q-Orbitrap HRMS metabolomics. Biodiversitas 22: 1535-1542. Ensuring consistency of quality, safety, and efficacy of herbal medicines from raw materials to finished products is important because of the variability in medicinal plants' active components. One of the plants that have been used as an antidiabetic herbal medicine is A. paniculata. This study aims to determine α-glucosidase inhibitory activity, the content of several metals, FTIR spectrum profile, and putative identification of A. paniculata metabolites using UHPLC-Q-Orbitrap HRMS from different geographical origin. We found that ethanol extract of A. paniculata gave higher inhibition of α-glucosidase activity compared to water extract. Eight metals were determined using FAAS and FAES, and calcium showed the highest content in all A. paniculata samples. FTIR spectra of A. paniculata showed a similar profile and only differed in the absorbance. We detected the presence of OH, C=O, C=C aromatic, and C-O functional groups in A. paniculata extract. About 32 metabolites were putatively identified in A. paniculata, mainly from phenolic and diterpene lactones class compounds based on UHPLC-Q-Orbitrap HRMS. Using a combination of FTIR spectra and peak area from 32 identified peaks, we can clustered A. paniculata based on its geographical origin. Based on the result obtained, the geographical origin of A. paniculata affected the metals and metabolites composition and level, resulting in different levels of α-glucosidase inhibitory activity.

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“…It was also reported that the extract of different plant materials possesses dissimilar organic compound which suggests that different plants have different potential in its capability to inhibit corrosion [14]. Kalmegh or also known as the "king of bitters" are categorized in the family Acanthaceae can be largely found in the region of tropical and subtropical Asia [15,16]. Growing in relatively high moistures and shady places, the extent of its height can reach up to 110 cm.…”

Section: Introductionmentioning

confidence: 99%

Evaluating the performance of Andrographis paniculata leaves extract as additive for corrosion protection of stainless steel 316L in seawater

2020

Int. J. Corros. Scale Inhib.

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Anti-corrosion protection coating serves as an effective way for the reduction of corrosion progress in a corrosive environment. With the increase of interest in green corrosion protection nowadays, Kalmegh or Andrographis paniculata from the family of Acanthaceae is evaluated for its potential as an additive in coating for stainless steel grade 316L (SS316L) via electrochemical impedance spectroscopy (EIS), potentiodynamic polarization (PP) and scanning electron microscope (SEM) in seawater. Characterization via Fourier transform infrared (FTIR) spectroscopy, Ultraviolet-Visible (UV-Vis) spectroscopy and High Performance Liquid Chromatography (HPLC) revealed the presence of asymmetry-NH,-CH and-OH, two peaks at 450 nm and 661 nm as well as the identification of andrographolide with a retention time of 4.650 min. Results showed an increase in corrosion resistance as the extract concentration in the coating increase. However, the efficiency was found to be limited at 10% extract concentration, and further increase diminished its inhibitive effect. Base on electrochemical analysis, coatings with the additive exhibited a mixed-type inhibitive property which was identified through the polarization curve. SEM micrograph of the coated steel surface showed inhomogeneous layers with rough structure possibly due to an aggressive attack of corrosive species in the medium on multiple sites.

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Identification of functional group present in Andrographis paniculata (kalmegh) leaves by FTIR analysis

Cited by 11 publications

References 7 publications

Methylene Blue Dye Degradation Using Silver Nanoparticles Synthesized from Andographis Paniculata Leaves Extract

Methylene Blue Dye Degradation Using Silver Nanoparticles Synthesized from Andographis Paniculata Leaves Extract

Inhibition of α-glucosidase activity, metals content, and phytochemical profiling of Andrographis paniculata from different geographical origins based on FTIR and UHPLC-Q-Orbitrap HRMS metabolomics

Evaluating the performance of Andrographis paniculata leaves extract as additive for corrosion protection of stainless steel 316L in seawater

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