Identification of gallic acid as a active ingredient of Syzygium aromaticum against tacrolimus-induced damage in renal epithelial LLC-PK1 cells and rat kidney

Lee, Ji Hwan; Park, Musun; Jung, Kiwon; Hong, Gyeongmin; Lee, Hye Lim; Kim, Dong-Wook; Kim, Chang-Eop; Kang, Ki Sung

doi:10.1016/j.bmcl.2021.128012

Cited by 4 publications

(2 citation statements)

References 50 publications

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“…Aqueous and ethanolic extract powders of dried Syzygium aromaticum buds include adequate gallic acids which are one of the considerable compounds of phenolic. It was shown to have a strong antioxidant impact of gallic acid on kidney dysfunction in rats [ 145 ]. Equisetum arvense L. with traces of alkaloids, flavonoids, triterpenoids, phytosterols is the most popular species from the Equisetum genus whose diuretic effects were confirmed in animal models and clinical trials [ 84 ].…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Classification of Medicinal Plants Used in the Treatment of Kidney Disease Based on Traditional Persian Medicine

Rabizadeh

Mirian

Doosti

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Background and Objectives. Human beings have used natural products as one of the pharmaceutical sources to improve human health for thousands of years. Phytochemical constituents distributed in different parts of medicinal plants cause therapeutic effects on treatment of acute and chronic diseases. Over the years, traditional Persian medicine has become popular over Iran and some countries globally as a source of alternative therapies of kidney diseases and renal dysfunctions. Iranian herbal medicine consists of natural compounds with complex active ingredients that causes valuable effects. Despite performing research works on traditional Persian medicine in the treatment of kidney disorders, there is still a need to investigate on chemical components and biological molecules of medicinal plants. Methods. This review was focused on studying the various secondary metabolites in model plants of Iranian herbal medicine known as treatment of kidney diseases in traditional Persian medicine textbooks including Makhzan-ol-Advieh, The Canon of Medicine, and Taghvim al-Abdan fi Tadbir al-Ensan. Results. Secondary metabolites of 94 medical plants belonging to 42 families were reported with their scientific and family name. Conclusion. Although herbal medicines are gaining rapid popularity among people and the pharmaceutical industry, the understandings of the phytochemical and therapeutic properties of medicinal plant are important for developing effective nephroprotective medicines. Therefore, the relationship between traditional uses and biological properties should be clearly verified through further studies.

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Section: Discussionmentioning

confidence: 99%

Phytochemical Classification of Medicinal Plants Used in the Treatment of Kidney Disease Based on Traditional Persian Medicine

Rabizadeh

Mirian

Doosti

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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“…Activities of important antioxidant enzymes such as SOD and catalase (CAT) were found to be significantly increased in all organs analyzed in the study as compared with the control ( Table 2 ) [ 96 ]. The study concluded that the significant antioxidant activity of UD leaves can be utilized in chemotherapy against multiple organs ( Figure 1 ) [ 96 , 97 , 98 ].…”

Section: Antioxidant Potential Of Udmentioning

confidence: 99%

Antioxidant Activity of Urtica dioica: An Important Property Contributing to Multiple Biological Activities

Jaiswal

Lee

2022

Antioxidants

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Urtica dioica (UD) is a multi-functional plant known to be used as both food and medicine from ancient times. The plant has the potential to be used as a fertilizer and for biological pest control. It is also used in textile and related industries for its quality fibers. In the recent past, the plant has received great attention for its numerous important biological activities and food applications. The antioxidant activity of UD is the crucial factor supporting its important biological activities, such as anticancer, antidiabetic and anti-inflammatory properties. The antioxidant activity of UD is also found to be protective in different organs, including the brain, liver, lungs, kidney, ovary, and uterus, and may also be protective against diseases associated with these organs. Few clinical studies have endorsed the antioxidant potential of UD in patients. The current work is an attempt to comprehensively compile and discuss the antioxidant activity of UD from in vitro, in vivo and human studies. The insights of the current study would be helpful in getting a panoramic view of the antioxidant potential of UD, and provide direction for optimizing and developing it for therapeutic applications against important diseases and conditions in the near future.

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An evaluative review on Stryphnodendron adstringens extract composition: Current and future perspectives on extraction and application

Ribeiro

Santos

Novais

et al. 2022

Industrial Crops and Products

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Identification of gallic acid as a active ingredient of Syzygium aromaticum against tacrolimus-induced damage in renal epithelial LLC-PK1 cells and rat kidney

Cited by 4 publications

References 50 publications

Phytochemical Classification of Medicinal Plants Used in the Treatment of Kidney Disease Based on Traditional Persian Medicine

Phytochemical Classification of Medicinal Plants Used in the Treatment of Kidney Disease Based on Traditional Persian Medicine

Antioxidant Activity of Urtica dioica: An Important Property Contributing to Multiple Biological Activities

An evaluative review on Stryphnodendron adstringens extract composition: Current and future perspectives on extraction and application

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