Identification of gene signatures and molecular mechanisms underlying the mutual exclusion between psoriasis and leprosy
You-Wang Lu,
Rong-Jing Dong,
Lu-Hui Yang
et al.
Abstract:Leprosy and psoriasis rarely coexist, the specific molecular mechanisms underlying their mutual exclusion have not been extensively investigated. This study aimed to reveal the underlying mechanism responsible for the mutual exclusion between psoriasis and leprosy. We obtained leprosy and psoriasis data from ArrayExpress and GEO database. Differential expression analysis was conducted separately on the leprosy and psoriasis using DEseq2. Differentially expressed genes (DEGs) with opposite expression patterns i… Show more
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