2022
DOI: 10.21203/rs.3.rs-2072898/v1
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Identification of key genes of anti-programmed death ligand 1 for meningioma immunotherapy by bioinformatic analysis

Abstract: Meningioma is one of the most common primary tumors in the central nervous system (CNS). A deeper understanding of its molecular characterization could provide potential therapeutic targets to reduce recurrence. In this study, we attempted to identify specific gene mutations in meningioma for immunotherapy. One GSE43290 dataset was obtained from the Gene Expression Omnibus (GEO) database to find differentially expressed genes (DEGs) between meningioma tissues and normal meninges. In total, 420 DEGs were identi… Show more

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