2024
DOI: 10.2147/pgpm.s449230
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Identification of Lower Grade Glioma Antigens Based on Ferroptosis Status for mRNA Vaccine Development

Zhenxiang Zhao,
Na Xing,
Hao Guo
et al.

Abstract: mRNA vaccines represent a promising and innovative strategy within the realm of cancer immunotherapy. However, their efficacy in treating lower-grade glioma (LGG) requires evaluation. Ferroptosis exhibits close associations with the initiation, evolution, and suppression of cancer. In this study, we explored the landscape of the ferroptosis-associated tumor microenvironment to facilitate the development of mRNA vaccines for LGG patients. Patients and Methods: Genomic and clinical data of the LGG patients was o… Show more

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