Identification of luteolin-7-glucoside metabolites after oral administration and development of a method for their quantitative analysis
G. V. Adamov,
O. L. Saybel,
A. N. Babenko
et al.
Abstract:Introduction. The development and registration of antiviral drugs is an urgent task. Flavonoids, in particular, luteolin-7-glycoside (cinaroside, luteolin-7-O-glycoside) demonstrate high broad-spectrum antiviral activity in vitro, and the industrial regulations for the production of luteolin-7-glycoside from the leaves of holly willow have already been developed at the VILAR. One of the problems with the introduction of flavonoids into medical practice is their low bioavailability and intensive biotransformati… Show more
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