2016
DOI: 10.1002/cne.24073
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Identification of novel candidate regulators of retinotectal map formation through transcriptional profiling of the chick optic tectum

Abstract: Information from the retina is carried along the visual pathway with accuracy and spatial conservation as a result of topographically mapped axonal connections. The optic tectum in the midbrain is the primary region to which retinal ganglion cells project their axons in the chick. The two primary axes of the retina project independently onto the tectum using different sets of guidance cues to give rise to the retinotectal map. Specificity of the map is determined by attractive or repulsive interactions between… Show more

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Cited by 2 publications
(1 citation statement)
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“…In the precocial chicken, all developmental steps must lead to a functional network before hatching. The chicken is a suitable and well-studied model for the cellular and molecular processes that establish the connections in the retino-tectal projection (Thanos and Mey, 2001 ; Kukreja et al, 2017 ) and the early auditory pathway (Kubke and & Carr, 2000 ). AP-2 is an important family of transcription factors implicated in many aspects of development, cell differentiation, and the regulation of cell growth and death (Hilger-Eversheim et al, 2000 ).…”
Section: Introductionmentioning
confidence: 99%
“…In the precocial chicken, all developmental steps must lead to a functional network before hatching. The chicken is a suitable and well-studied model for the cellular and molecular processes that establish the connections in the retino-tectal projection (Thanos and Mey, 2001 ; Kukreja et al, 2017 ) and the early auditory pathway (Kubke and & Carr, 2000 ). AP-2 is an important family of transcription factors implicated in many aspects of development, cell differentiation, and the regulation of cell growth and death (Hilger-Eversheim et al, 2000 ).…”
Section: Introductionmentioning
confidence: 99%