Identification of porcine circovirus-3 in Mozambique

Anahory, Iolanda Vieira; Franzo, Giovanni; Settypalli, Tirumala Bharani Kumar; Mapaco, Lourenço; Achá, Sara J.; Molini, Umberto; Cattoli, Giovanni; Lamien, Charles Euloge; Dundon, William G.

doi:10.1007/s11259-021-09858-4

Cited by 11 publications

(10 citation statements)

References 16 publications

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“…Positive rates in China have shown significant fluctuations (ranging from 10 to 60%), with some farms even recording a 100% rate ( 13 , 51–57 ). Anahory et al ( 58 ) analyzed 172 archived DNA samples consisting of spleen, tonsils, liver, and ganglia collected from 91 pigs in nine of the ten provinces of Mozambique between 2011 and 2019. Their analysis provided the first evidence of PCV3 presence in Africa, with a total of 7 (7.5%) positive animals ( Figure 2 ).…”

Section: Epidemiologymentioning

confidence: 99%

“…Other studies have reported triple co-infections involving PCV3, PCV2, and PRRSV; PCV3, PCV1, and PCV2; and PCV3, TTSuV1, and TTSuV2, with prevalence rates of 1.9, 3.6, and 50%, respectively ( 31 , 56 , 91 ). Moreover, the recent discovery of PCV3 in Mozambique, Africa revealed co-infection with the African Swine Fever Virus (ASFV), where 6 out of 7 positive PCV3 samples also tested positive for ASFV (6.5% of total samples) ( 58 ) ( Figure 4 ).…”

Section: Coinfectionsmentioning

confidence: 99%

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Porcine circovirus 3: a new challenge to explore

Silva,

Silva

et al. 2024

Front. Vet. Sci.

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The intensification of production processes, resulting from the rise in pork production, contributes to environmental changes and increased interaction between humans, animals, and wildlife. This favorable scenario promotes the spread of potent viral species, such as PCV3, increasing the potential for the emergence of new pathogenic agents and variants. These changes in the epidemiology and manifestation of PCV3 highlight the need for enhanced understanding and control. The current literature presents challenges in the classification of PCV3, with different groups proposing diverse criteria. Establishing common terminology is crucial to facilitate comparisons between studies. While consensus among experts is valuable, new approaches must be transparent and comparable to existing literature, ensuring reproducible results and proper interpretation, and positively impacting public health. This study aims to review the literature on PCV3 infection, exploring its key aspects and highlighting unanswered questions.

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Section: Epidemiologymentioning

confidence: 99%

Section: Coinfectionsmentioning

confidence: 99%

Porcine circovirus 3: a new challenge to explore

Silva,

Silva

et al. 2024

Front. Vet. Sci.

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“…Recent data indicate that coinfection with PCVs and ASFV is possible, at least in domestic pigs, which was confirmed with PCV2 in Mongolia [19], and with PCV3 in Mozambique [20] and Nigeria [21]. It is still unclear whether PCV2 or PCV3 infection predisposed the pigs to the ASFV infection, and that subject requires further analysis [19][20][21]. In both cases, the samples originated from domestic pigs, and there is still no data on ASFV coinfection with PCVs in wild boars.…”

Section: Introductionmentioning

confidence: 99%

Porcine Circovirus Type 3 (PCV3) in Poland: Prevalence in Wild Boar Population in Connection with African Swine Fever (ASF)

Frant,

Mazur-Panasiuk,

Gal-Cisoń

et al. 2024

Viruses

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Human health is dependent on food safety and, therefore, on the health of farm animals. One of the most significant threats in regard to swine diseases is African swine fever (ASF). Infections caused by porcine circoviruses (PCVs) represent another important swine disease. Due to the ubiquitous nature of PCV2, it is not surprising that this virus has been detected in ASFV-affected pigs. However, recent data indicate that coinfection of PCV3 and ASFV also occurs. It is still unclear whether PCV infection plays a role in ASFV infection, and that subject requires further analysis. The aim of this study was to assess whether PCV3 and PCV4 are present in the wild boar population in Poland (real-time PCR). The analysis was performed on wild boar samples collected for routine ASF surveillance in Poland, between 2018 and 2021. By extension, the obtained data were compared in regard to ASFV presence in these samples, thus investigating the odds of ASFV infection on the grounds of the PCV carrier state in free-ranging Suidae in Poland. In addition, sequencing of PCV3 and phylogenetic analysis were performed, based on a full genome and a capsid gene. In the current study, we demonstrated the high prevalence of PCV3 in the wild boar population in Poland; meanwhile, PCV4 was not detected. The odds of ASFV infection on the grounds of the PCV3 carrier state in free-ranging Suidae in Poland was more than twice as high. Ten full genome sequences of PCV3 were obtained, all of them belonging to clade 3a. The similarity between them was in the range of 98.78–99.80%.

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“…There is growing information on the presence of PCV-2 and PCV-3 in Africa with viruses having been identified and characterized in several countries [ 2 , 6 , 10 , 12 ]. This is providing a clearer picture on the distribution of these viruses on the continent.…”

mentioning

confidence: 99%

“…The DNA samples were screened for PCV-2 and PCV-3 as previously described [ 2 , 10 ]. Positive amplicons of a segment of the ORF2 gene were purified and sequenced by LGC genomics (Berlin).…”

mentioning

confidence: 99%

Molecular characterization of porcine circovirus-2 and -3 in pigs in Tanzania

CHANG’A¹,

BITANYI²,

KAMIGWE³

et al. 2023

The Journal of Veterinary Medical Science

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Like in many other African countries, pig production is increasing in Tanzania. To support farmers and stakeholders, it is important to increase our understanding of porcine pathogens present in the country. Currently, little is known about the circulation of porcine circovirus-2 (PCV-2) and porcine circovirus-3 (PCV-3). For this reason, samples from 124 pigs collected throughout the country between 2018 to 2022 were screened by PCR for the presence of PCV-2 and PCV-3. Sequencing and phylogenetic analysis of positive amplicons identified two PCV-2 genotypes (a and d). Limited genetic heterogenicity was observed among the PCV-3. This study provides important data on pathogens present in pigs in Tanzania and should be of use veterinary authorities involved in porcine disease management.

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Identification of porcine circovirus-3 in Mozambique

Cited by 11 publications

References 16 publications

Porcine circovirus 3: a new challenge to explore

Porcine circovirus 3: a new challenge to explore

Porcine Circovirus Type 3 (PCV3) in Poland: Prevalence in Wild Boar Population in Connection with African Swine Fever (ASF)

Molecular characterization of porcine circovirus-2 and -3 in pigs in Tanzania

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