Identification of positively selected genes in Mycobacterium tuberculosis from southern Xinjiang Uygur autonomous region of China
Lele Deng,
Quan Wang,
Haican Liu
et al.
Abstract:BackgroundTuberculosis (TB), mainly caused by Mycobacterium tuberculosis (Mtb), remains a serious public health problem. Increasing evidence supports that selective evolution is an important force affecting genomic determinants of Mtb phenotypes. It is necessary to further understand the Mtb selective evolution and identify the positively selected genes that probably drive the phenotype of Mtb.MethodsThis study mainly focused on the positive selection of 807 Mtb strains from Southern Xinjiang of China using wh… Show more
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