Identification of quinoline, carboline and glycinamide compounds in cow milk using HRMS and NMR

Synthesis and characterization of some new organotellurium compounds based on quinoline

“…One set corresponds to the protons in the benzene ring (H5-H8) and the second set corresponds to the protons in the pyridine ring (H2-H4). The chemical shifts and coupling constant differences between the protons of benzene and pyridine rings of quinolone can found in reference [19][20][21]. The H2 proton of compounds 1-10 has the highest chemical shift, owing to deshielding by the proximal electronegative nitrogen, whereas the H3 has the lowest chemical shift.…”

“…So, the 1 H NMR spectra of compounds 1-10 show a doublet signal centered at δ 8.64-930 ppm range with J-J coupling constant ranged at 8 Hz (except 9 J-J constant = 12) can be attributed to H4 proton while a doublet signal centered at δ 8.12-8.49 ppm with J-J coupling = 8 Hz assign to H5. The last doublet signal which appeared at the range δ 8.19-8.37 ppm with J-J coupling equal to 8 Hz can be attributed to H7 proton [19,21]. Finally, a triplet signal centered at δ 7.90-8.23 ppm with J-J coupling = 8 Hz corresponds to H6 [19][20][21].…”

“…The last doublet signal which appeared at the range δ 8.19-8.37 ppm with J-J coupling equal to 8 Hz can be attributed to H7 proton [19,21]. Finally, a triplet signal centered at δ 7.90-8.23 ppm with J-J coupling = 8 Hz corresponds to H6 [19][20][21].…”

“…Quinoline is a hetero aromatic compound, so the n → π* and the π → π* transitions are expected to be shown, however the band due to the n → π* transition is generally weak, while the bands associated with the π → π* transitions do not present fine structure and are observed in two regions, which cover up the band owed to the n → π* transition and showed two maximum absorption peaks at 330 and 263 nm. The absorption at the long wavelength is characterized to present vibrational fine structure dependent on the physical state and solvent polarity [2,21]. In comparison with the compounds 1-7 , it is possible to verify that the maximum peak at 261 nm for the free quinoline is red-shifted (about 5-13 nm), as 268 nm for compounds 1 and 2; 274 nm for compounds 3 and 7; 270 nm for compound 4; 276 nm for compound 5; and 272 nm for compound 6.…”

Future perspectives in Orbitrap™-high-resolution mass spectrometry in food analysis: a review

“…The aglycones (genistein, daidzein, glycitein and biochanin A) as well as their three conjugated forms, beta-glucosides (genistin, daizin and glycitin) were detected and quantified Toro-Funes et al (2012). developed an UHPLC method with UV detection and Orbitrap MS confirmation for the simultaneous determination of isoflavone aglycones (daidzein, glycitein and genistein), their corresponding glycoside forms (daidzin, glycitin and genistin), and acetyl and malonyl conjugate forms of glycosides(malonyldaidzin, malonylglycitin, malonylgenistin, acetyldaidzin, acetylglycitin, acetylgenistin) in soy milk Rouge et al (2013). characterised new UV-absorbing compounds in cow's milk to gain an overview of the molecular diversity of minor bioactive constituents that could be used to trace animal feed or that potentially affect milk quality.…”