Identification of Seoul Hantavirus in Rattus norvegicus in Indonesia

Plyusnina, Angelina; Ibrahim, Ima-Nurisa; Winoto, Imelda; Porter, Kevin R.; Gotama, Ida Bagus Indra; Lundkvist, Åke; Vaheri, Antti; Plyusnin, Alexander

doi:10.1080/00365540410019264

Cited by 39 publications

(39 citation statements)

References 11 publications

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“…The clinical symptoms were mainly consistent with mild forms of HFRS but exact type(s) of the hantaviruses involved remained unknown at that time. Later, the first confirmation of human SEOV infection was obtained (see Plyusnina et al, 2004). In this study, we continued our analyses of hantavirus-infected rodents and found a novel hantavirus in Asian house rats R. tanezumi.…”

supporting

confidence: 55%

“…These two sibling species can be differentiated, e.g. by chromosomal or electrophoretic protein analysis] and Rattus exulans in several provinces (Ibrahim et al, 1996;Plyusnina et al, 2004). The Seoul virus (SEOV) genome sequence was recovered from R. norvegicus captured in Jakarta (Plyusnina et al, 2004).…”

mentioning

confidence: 99%

“…by chromosomal or electrophoretic protein analysis] and Rattus exulans in several provinces (Ibrahim et al, 1996;Plyusnina et al, 2004). The Seoul virus (SEOV) genome sequence was recovered from R. norvegicus captured in Jakarta (Plyusnina et al, 2004). Human cases associated with hantaviruses in Indonesia have also been reported (Groen et al, 2002).…”

mentioning

confidence: 99%

“…Lung tissue samples from four hantavirus antibody positive R. tanezumi that were captured in Serang, Banten Province in 2000, were screened for the presence of hantavirus nucleoprotein antigen (N-Ag) using immunoblotting as described previously (Plyusnina et al, 2004). The samples had been negative when tested with anti-Dobrava virus antiserum (which we routinely use to screen samples from mice and rats), but when retested with the serum collected from a SEOV-infected Norway rat, two samples were found weakly N-Ag positive.…”

mentioning

confidence: 99%

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A newly recognized hantavirus in the Asian house rat (Rattus tanezumi) in Indonesia

Plyusnina

Ibrahim

Plyusnin

2009

Journal of General Virology

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supporting

confidence: 55%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

A newly recognized hantavirus in the Asian house rat (Rattus tanezumi) in Indonesia

Plyusnina

Ibrahim

Plyusnin

2009

Journal of General Virology

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“…In other East Asian countries, such as Thailand, Indonesia, Vietnam, Sri Lanka and India, prevalence of SEOV and THAIV infection has been shown among rodents and humans [2,3,6,13,14,16,17,22].…”

mentioning

confidence: 99%

Studies on Hantavirus Infection in Small Mammals Captured in Southern and Central Highland Area of Vietnam

Luan

Yoshimatsu

Endo

et al. 2012

The Journal of Veterinary Medical Science

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ABSTRACT. To investigate the distribution of hantaviruses among animals in Southern and Central Highland area of Vietnam, a total of 1311 serum samples were obtained from rats and Asian house shrews (Suncus murinus) captured at 11 locations between 2006 and 2009. A total of 1066 serum samples from rats were examined for IgG antibodies against Hantaan virus, and there were 30 antibody-positive serum samples from rats that had been captured mainly in a port area and urban area in Ho Chi Minh City (HCMC) (2.8%). All of the antibody-positive rats were Rattus norvegicus, and they had Seoul virus (SEOV) genome in their lungs. SEOV sequences detected from rats captured in Southern Vietnam belonged to the same lineage as those from rats captured at Haiphong Port and a market area in Hanoi City. SEOV strain CSG5 was isolated from a rat captured at Saigon Harbor. Strain CSG5 showed a cross-neutralization pattern almost the same as that of a representative strain of SEOV. A total of 245 Asian house shrews were captured in the Central Highland area and near HCMC. Sera were examined for IgG antibodies against Thottapalayam virus (TPMV), and 32 (13.1%) of the antibody-positive shrews were mainly from the Central Highland area and showed a neutralizing antibody against TPMV. These results indicated that SEOV is distributed among R. norvegicus inhabiting harbor and urban areas of Southern Vietnam and that TPMV or an antigenically related virus is distributed among Asian house shrews in Central Highland area.

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Hantaviruses in small mammals and humans in the coastal region of Zhejiang Province, China

Zhāng

Lin

Shi³

et al. 2010

Journal of Medical Virology

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To gain more insights into the epidemiology of hantaviruses in the coastal region of Zhejiang Province, China, the morbidity and mortality of hemorrhagic fever with renal syndrome (HFRS) were analyzed in two coastal areas: Cixi (hilly terrain) and Wenzhou (mountainous terrain). More HFRS cases have been reported in Cixi than in Wenzhou. Annual incidence rate of HFRS in Cixi had been on the level of approximately 1.5/100,000 from 1968 (when the first HFRS case was reported) to 2007, with the highest incidence rate of 8.54/100,000 in 1999. The annual incidence rate in Wenzhou has been relatively low, less than 0.5/100,000 since the first HFRS case was reported in 1981. A total of 461 rodents and 199 shrews were captured in these two areas. Hantavirus antibodies were detected in 16 of 241 (6.64%) Rattus norvegicus and 13 of 122 (10.66%) R. flavipectus. Interestingly, hantavirus antigens were identified in 6 of 196 (3.06%) Suncus murinus. Genetic analysis showed that partial M and S segment sequences recovered from rats in the two regions belong to Seoul virus (SEOV) and can be assigned into two genetic lineages. SEOV variants that belong to these two lineages of viruses are distributed widely in China and have been found outside China. As most trapped rodents were rats and SEOV was the only hantavirus detected, these results suggested that SEOV plays an important role in human hantavirus infections. They also reinforce the need for vigilance in preventing HFRS caused by hantaviruses in the coastal region.

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Identification of Seoul Hantavirus in Rattus norvegicus in Indonesia

Cited by 39 publications

References 11 publications

A newly recognized hantavirus in the Asian house rat (Rattus tanezumi) in Indonesia

A newly recognized hantavirus in the Asian house rat (Rattus tanezumi) in Indonesia

Studies on Hantavirus Infection in Small Mammals Captured in Southern and Central Highland Area of Vietnam

Hantaviruses in small mammals and humans in the coastal region of Zhejiang Province, China

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