Secondary metabolites of bacteria can be used to control
microorganisms. In this study, the antimicrobial activity
properties of Bacillus isolates from Apis mellifera and Varroa
destructor have been determined. The antimicrobial activities
of Bacillus species against some bacteria and pathogenic yeast
(Candida albicans) were investigated according to the disc
diffusion method. As a result of the research, secondary
metabolites of Bacillus isolates used in the study inhibited the
development of the tested microorganisms at different rates
(1.1-8.4 mm inhibition zone). Two isolates GAP2 (Bacillus
subtilis) and GAP9 (Bacillus thuringiensis) showed high
antibacterial activity. Most of the metabolites isolated from
bacterial isolates were shown to be sensitive to Escherichia coli
ATCC2471 and Serratia marcescens ATCC13880 (p