Identification, quantification, and prioritization of new emerging pollutants in domestic and industrial effluents, Korea: Application of LC-HRMS based suspect and non-target screening

Choi, Young-Hun; Lee, Ji-Ho; Kim, Kyunghyun; Mun, Hyunsaing; Naree, Park; Jeon, Junho

doi:10.1016/j.jhazmat.2020.123706

Cited by 67 publications

(20 citation statements)

References 50 publications

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“…Pollution derived from natural sources, e.g., volcanoes, can move to spread and vanish in a short time, likely posing limited concerns to human health [ 69 ]. On the contrary, contamination derived from anthropogenic activities led to persistent environmental poisoning due to the release of either organic (e.g., bisphenols, plastics, fertilizers, pesticides) or inorganic pollutants, including heavy metals and metalloids (e.g., Cd, Cu, As, Zn, Hg, Pb) [ 70 ], as well as new emerging pollutants (e.g., nano/microplastics, pharmaceuticals, personal care products, surfactants, fire retardants, and so on) leading to an ever-increasing concern for of all trophic levels [ 71 ].…”

Section: Nanoremediation Of Contaminated Soilsmentioning

confidence: 99%

Nano-Enable Materials Promoting Sustainability and Resilience in Modern Agriculture

et al. 2021

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Intensive conventional agriculture and climate change have induced severe ecological damages and threatened global food security, claiming a reorientation of agricultural management and public policies towards a more sustainable development model. In this context, nanomaterials promise to support this transition by promoting mitigation, enhancing productivity, and reducing contamination. This review gathers recent research innovations on smart nanoformulations and delivery systems improving crop protection and plant nutrition, nanoremediation strategies for contaminated soils, nanosensors for plant health and food quality and safety monitoring, and nanomaterials as smart food-packaging. It also highlights the impact of engineered nanomaterials on soil microbial communities, and potential environmental risks, along with future research directions. Although large-scale production and in-field testing of nano-agrochemicals are still ongoing, the collected information indicates improvements in uptake, use efficiency, targeted delivery of the active ingredients, and reduction of leaching and pollution. Nanoremediation seems to have a low negative impact on microbial communities while promoting biodiversity. Nanosensors enable high-resolution crop monitoring and sustainable management of the resources, while nano-packaging confers catalytic, antimicrobial, and barrier properties, preserving food safety and preventing food waste. Though, the application of nanomaterials to the agri-food sector requires a specific risk assessment supporting proper regulations and public acceptance.

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Section: Nanoremediation Of Contaminated Soilsmentioning

confidence: 99%

Nano-Enable Materials Promoting Sustainability and Resilience in Modern Agriculture

et al. 2021

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“…In this study, a scoring system was designed to highlight the most significant natural toxins of concern in drinking water reservoirs. The scoring system was in accordance with the previous protocol that was published by Choi et al [31], which is based on the risk-relevant parameters such as the detection frequency in percentage, biodegradability, log BAF, and the toxicity values based on the 50% lethal dose (LD50) laboratory tests in mice. A score in the range of 0 to 100 for each parameter was used, and 100 points were additionally added if carcinogenicity or neurotoxicity was already reported for the substance as what happens, for example, with AflB 1 and AflB 2 .…”

Section: Prioritisationmentioning

confidence: 99%

Suspect and Target Screening of Natural Toxins in the Ter River Catchment Area in NE Spain and Prioritisation by Their Toxicity

Picardo

Núñez

Farré

2020

Toxins

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This study presents the application of a suspect screening approach to screen a wide range of natural toxins, including mycotoxins, bacterial toxins, and plant toxins, in surface waters. The method is based on a generic solid-phase extraction procedure, using three sorbent phases in two cartridges that are connected in series, hence covering a wide range of polarities, followed by liquid chromatography coupled to high-resolution mass spectrometry. The acquisition was performed in the full-scan and data-dependent modes while working under positive and negative ionisation conditions. This method was applied in order to assess the natural toxins in the Ter River water reservoirs, which are used to produce drinking water for Barcelona city (Spain). The study was carried out during a period of seven months, covering the expected prior, during, and post-peak blooming periods of the natural toxins. Fifty-three (53) compounds were tentatively identified, and nine of these were confirmed and quantified. Phytotoxins were identified as the most frequent group of natural toxins in the water, particularly the alkaloids group. Finally, the toxins identified to levels 2 and 1 were prioritised according to their bioaccumulation factor, biodegradability, frequency of detection, and toxicity. This screening and prioritisation approach resulted in different natural toxins that should be further assessed for their ecotoxicological effects and considered in future studies.

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“…In the last few years, Ultra-High Performance Liquid chromatography (UHPLC) coupled to tandem MS (MS/MS), or to high-resolution MS (HRMS), have been widely used for accurate quantification of organic micropollutants ( Boix et al, 2014 ;Gracia-Lor et al, 2011 ), or for widescope screening ( Guardian et al, 2021 ;Hernández et al, 2015bHernández et al, , 2015Llorca et al, 2021 ;Lotfi Khatoonabadi et al, 2021 ), respectively. The latter allows the full-data acquisition of all the ionizable compounds present in the sample, enabling the possibility to perform target, suspect or non-target screening, also in a retrospective way ( Choi et al, 2021 ;Hollender et al, 2017 ;Menger et al, 2020 ). The accurate-mass full-spectrum acquisition is highly valuable for the identification of suspect compounds, such as metabolites and transformation products, as there are not analytical reference standards available for many of them, and therefore identification must be based on accurate mass fragmentation ( Boix et al, 2016a( Boix et al, , 2016, among other MS data.…”

Section: Introductionmentioning

confidence: 99%

Wide-scope screening of pharmaceuticals, illicit drugs and their metabolites in the Amazon River

Fabregat‐Safont¹,

Ibáñez²,

Bijlsma³

et al. 2021

Water Research

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Only a limited number of households in the Amazon are served by sewage collection or treatment facilities, suggesting that there might be a significant emission of pharmaceuticals and other wastewater contaminants into freshwater ecosystems. In this work, we performed a wide-scope screening to assess the occurrence of pharmaceuticals, illicit drugs and their metabolites in freshwater ecosystems of the Brazilian Amazon. Our study included 40 samples taken along the Amazon River, in three of its major tributaries, and in small tributaries crossing four important urban areas (Manaus, Santarém, Macapá, Belém). More than 900 compounds were investigated making use of target and suspect screening approaches, based on liquid chromatography coupled to high-resolution mass spectrometry with ion mobility separation. Empirical collision-cross section (CCS) values were used to help and confirm identifications in target screening, while in the suspect screening approach CCS values were predicted using Artificial Neural Networks to increase the confidence of the tentative identification. In this way, 51 compounds and metabolites were identified. The highest prevalence was found in streams crossing the urban areas of Manaus, Macapá and Belém, with some samples containing up to 30 -40 compounds, while samples taken in Santarém showed a lower number (8 -11), and the samples taken in the main course of the Amazon River and its tributaries contained between 1 and 7 compounds. Most compounds identified in areas with significant urban impact belonged to the analgesics and antihypertensive categories, followed by stimulants and antibiotics. Compounds such as caffeine, cocaine and its metabolite benzoylecgonine, and cotinine (the metabolite of nicotine), were also detected in areas with relatively low anthropogenic impact and showed the highest total prevalence. This study supports the need to improve the sanitation system of urban areas in the Brazilian Amazon and the development of follow-up studies aimed at quantifying exposure levels and risks for Amazonian freshwater biodiversity.

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Identification, quantification, and prioritization of new emerging pollutants in domestic and industrial effluents, Korea: Application of LC-HRMS based suspect and non-target screening

Cited by 67 publications

References 50 publications

Nano-Enable Materials Promoting Sustainability and Resilience in Modern Agriculture

Nano-Enable Materials Promoting Sustainability and Resilience in Modern Agriculture

Suspect and Target Screening of Natural Toxins in the Ter River Catchment Area in NE Spain and Prioritisation by Their Toxicity

Wide-scope screening of pharmaceuticals, illicit drugs and their metabolites in the Amazon River

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