Identifying and improving non‐adherence in bipolar disorders

Colom, Francesc; Vieta, Eduard; Tacchi, MJ; Sanchez-Moreno, José; Scott, Jan

doi:10.1111/j.1399-5618.2005.00248.x

Cited by 157 publications

(145 citation statements)

References 67 publications

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“…'adherence') or definition meets all needs of the field [115][116][117][118][119][120][121][122][123][124][125][126][127][128]. There is thus a clear need to create an agreed set of rules [129], within which future activities can fit, to provide concise and adequate definitions and an associated conceptual framework that could serve the needs of both clinical research and medical practice [129,130].…”

Section: Sackett and Haynes (1976) [64]mentioning

confidence: 99%

A New Taxonomy for Describing and Defining Adherence to Medications

Vrijens

Geest

Hughes

et al. 2011

British Journal of Clinical Pharmacology

232

316

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Interest in patient adherence has increased in recent years, with a growing literature that shows the pervasiveness of poor adherence to appropriately prescribed medications. However, four decades of adherence research has not resulted in uniformity in the terminology used to describe deviations from prescribed therapies. The aim of this review was to propose a new taxonomy, in which adherence to medications is conceptualized, based on behavioural and pharmacological science, and which will support quantifiable parameters. A systematic literature review was performed using MEDLINE, EMBASE, CINAHL, the Cochrane Library and PsycINFO from database inception to 1 April 2009. The objective was to identify the different conceptual approaches to adherence research. Definitions were analyzed according to time and methodological perspectives. A taxonomic approach was subsequently derived, evaluated and discussed with international experts. More than 10 different terms describing medication-taking behaviour were identified through the literature review, often with differing meanings. The conceptual foundation for a new, transparent taxonomy relies on three elements, which make a clear distinction between processes that describe actions through established routines ('Adherence to medications' , 'Management of adherence') and the discipline that studies those processes ('Adherence-related sciences'). 'Adherence to medications' is the process by which patients take their medication as prescribed, further divided into three quantifiable phases: 'Initiation' , 'Implementation' and 'Discontinuation' . In response to the proliferation of ambiguous or unquantifiable terms in the literature on medication adherence, this research has resulted in a new conceptual foundation for a transparent taxonomy. The terms and definitions are focused on promoting consistency and quantification in terminology and methods to aid in the conduct, analysis and interpretation of scientific studies of medication adherence.

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Section: Sackett and Haynes (1976) [64]mentioning

confidence: 99%

A New Taxonomy for Describing and Defining Adherence to Medications

Vrijens

Geest

Hughes

et al. 2011

British Journal of Clinical Pharmacology

232

316

View full text Add to dashboard Cite

show abstract

“…Since in our results there was an improvement in both fields, the fact that medication adherence helps habits regularization should not be entirely ruled out (Chatterton et al, 2017;Colom et al, 2005b;Wenze et al, 2016). Similarly, we should not discard the opposite: the patient becoming more adherent by means of being more regular, as many medication intakes are linked to a very specific routine (i.e., taking the pills immediately before meals, or when brushing teeth, etc.).…”

Section: Discussionmentioning

confidence: 89%

Is a SIMPLe smartphone application capable of improving biological rhythms in bipolar disorder?

Hidalgo‐Mazzei

Reinares

Mateu

et al. 2017

Journal of Affective Disorders

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“…60% of patients with BD reported that they withdraw from medication in six months (1). More than one-third of bipolar patients discontinue the medication at least twice and nine of ten bipolar patients admitted they discontinue the medication at least once in their lives (8).…”

Section: Assessment Of Treatment Adherence In Patients With Bipolar Dmentioning

confidence: 99%

Assessment of Treatment Adherence in Patients with Bipolar Disorder

Karaytuğ¹,

Keskin²,

Tamam³

et al. 2017

JMOOD

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Objective: Non-adherence with medication is very common in patients with Bipolar Disorder (BD) and is the most frequent cause of recurrence. The aim of this study was to assess treatment adherence and related demographic and clinical factors in patients with bipolar disorder. Manual of Mental Disorders, fourth edition (DSM-IV) Axis II (SCID-II) was used to determine the comorbidity of personality disorders. Well, moderately, and poorly adherent patients were compared with respect to clinical and socio-demographic variables and functionality scores. Results:The rate of moderately and poorly adherent patients was 70.6% of the sample. Married patients and patients with social support were more adherent. The rate of previous suicide attempt was higher in well adherers. Comorbidity with personality disorders, alcohol and substance use, and the type of treatment were not associated with adherence. Conclusions:The results of this study have shown that being single and lacking social support were the factors that have the most significant effect on treatment adherence. Good adherers may have a better outcome, so patients with BD especially who do not have efficient social support should be monitored for treatment adherence closely.

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Identifying and improving non‐adherence in bipolar disorders

Cited by 157 publications

References 67 publications

A New Taxonomy for Describing and Defining Adherence to Medications

A New Taxonomy for Describing and Defining Adherence to Medications

Is a SIMPLe smartphone application capable of improving biological rhythms in bipolar disorder?

Assessment of Treatment Adherence in Patients with Bipolar Disorder

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