2021
DOI: 10.3389/fdata.2020.528828
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Identifying Clinical and Genomic Features Associated With Chronic Kidney Disease

Abstract: We apply a pattern-based classification method to identify clinical and genomic features associated with the progression of Chronic Kidney disease (CKD). We analyze the African-American Study of Chronic Kidney disease with Hypertension dataset and construct a decision-tree classification model, consisting 15 combinatorial patterns of clinical features and single nucleotide polymorphisms (SNPs), seven of which are associated with slow progression and eight with rapid progression of renal disease among African-A… Show more

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Cited by 1 publication
(2 citation statements)
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“…By considering the occurrence of kidney impairment called albuminuria, the doctors confirm CKD by gathering glomerular filter rate (GFR) within 3 months 15 . CKD indicates a damaged form of kidneys that cannot perform blood filtering in a normal way.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…By considering the occurrence of kidney impairment called albuminuria, the doctors confirm CKD by gathering glomerular filter rate (GFR) within 3 months 15 . CKD indicates a damaged form of kidneys that cannot perform blood filtering in a normal way.…”
Section: Introductionmentioning
confidence: 99%
“…By considering the occurrence of kidney impairment called albuminuria, the doctors confirm CKD by gathering glomerular filter rate (GFR) within 3 months. 15 CKD indicates a damaged form of kidneys that cannot perform blood filtering in a normal way. The irreversible and progressive weakening of kidney functionalities tends to cause CKD, particularly the glomerular filtration rate degradation over several years or months.…”
mentioning
confidence: 99%